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Clinical trial

Node-Sparing Short-Course Radiotherapy Plus Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer: An Open-Label, Randomized, Prospective Phase II/III Trial (MODIFI-RC-II)

NCT06958432 is registered in ClinicalTrials.gov with Sixth Affiliated Hospital, Sun Yat-sen University as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Node-Sparing Short-Course Radiotherapy Plus Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer: An Open-Label, Randomized, Prospective Phase II/III Trial (MODIFI-RC-II)
Lead sponsor
Sixth Affiliated Hospital, Sun Yat-sen University
Phase
Phase 2/3
Overall status
Recruiting
Start date
May 6, 2025
Completion date
December 31, 2031
Enrollment
430 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

immune checkpoint therapy, neoadjuvant therapies, radiotherapy, rectal cancer