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Clinical trial

A National Multicenter, Randomized, Placebo-Controlled Phase III Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer

NCT07113275 is registered in ClinicalTrials.gov with Tao Zhang as lead sponsor.

NCT NCT07113275
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Registry record

As filed in ClinicalTrials.gov.

Title
A National Multicenter, Randomized, Placebo-Controlled Phase III Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer
Lead sponsor
Tao Zhang
Phase
Phase 3
Overall status
Recruiting
Start date
May 15, 2026
Completion date
December 31, 2028
Enrollment
444 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

immunotherapy, radiotherapy, rectal cancer, total neoadjuvant therapy