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Clinical trial

Phase I Clinical Trial of Caring Cross Anti-CD19/20/22 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Lymphoid Malignancies (Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia) (C3PO)

NCT07166419 is registered in ClinicalTrials.gov with Ohio State University Comprehensive Cancer Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase I Clinical Trial of Caring Cross Anti-CD19/20/22 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Lymphoid Malignancies (Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia) (C3PO)
Lead sponsor
Ohio State University Comprehensive Cancer Center
Phase
Phase 1
Overall status
Active, not recruiting
Start date
January 14, 2026
Completion date
December 31, 2026
Enrollment
24 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

blast phase chronic myeloid leukemia, bcr-abl1 positive, recurrent acute lymphoblastic leukemia, recurrent chronic lymphocytic leukemia, recurrent chronic myeloid leukemia, bcr-abl1 positive, recurrent indolent non-hodgkin lymphoma, recurrent lymphoblastic lymphoma, recurrent non-hodgkin lymphoma, recurrent transformed chronic lymphocytic leukemia, refractory acute lymphoblastic leukemia, refractory chronic lymphocytic leukemia, refractory chronic myeloid leukemia, bcr-abl1 positive, refractory indolent non-hodgkin lymphoma, refractory lymphoblastic lymphoma, refractory non-hodgkin lymphoma, refractory transformed chronic lymphocytic leukemia