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Clinical trial

Phase II Single Arm Study of Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer: the CHIMERA Study.

NCT07407465 is registered in ClinicalTrials.gov with Gruppo Oncologico del Nord-Ovest as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase II Single Arm Study of Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer: the CHIMERA Study.
Lead sponsor
Gruppo Oncologico del Nord-Ovest
Phase
Phase 2
Overall status
Recruiting
Start date
October 20, 2025
Completion date
October 20, 2027
Enrollment
42 (estimated)
Sites
28

Conditions

As the registry lists them; a condition with its own page is linked.

colon cancer adenocarcinoma, colon cancer metastatic, colorectal adenocarcinoma, colorectal cancer, rectal adenocarcinoma, rectal cancer, adenocarcinoma, rectal cancer, metastatic