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Clinical trial

RASolute 305: A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherapy (Modified FOLFIRINOX or Gemcitabine Plus Nab-Paclitaxel) With or Without Zoldonrasib (RMC-9805) as First-line Treatment in Patients With Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma

NCT07621718 is registered in ClinicalTrials.gov with Revolution Medicines, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
RASolute 305: A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherapy (Modified FOLFIRINOX or Gemcitabine Plus Nab-Paclitaxel) With or Without Zoldonrasib (RMC-9805) as First-line Treatment in Patients With Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma
Lead sponsor
Revolution Medicines, Inc.
Phase
Phase 3
Overall status
Recruiting
Start date
May 22, 2026
Completion date
April 22, 2030
Enrollment
670 (estimated)
Sites
19

Conditions

As the registry lists them; a condition with its own page is linked.

pancreatic adenocarcinoma, pancreatic adenocarcinoma metastatic, pancreatic adenosquamous carcinoma, pancreatic cancer, pancreatic cancer metastatic, pancreatic ductal adenocarcinoma (pdac), pdac, pdac - pancreatic ductal adenocarcinoma