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Clinical trial

Phase 1/1b, Multicenter, Open-Label, Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

NCT07349537 is registered in ClinicalTrials.gov with Revolution Medicines, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase 1/1b, Multicenter, Open-Label, Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
Lead sponsor
Revolution Medicines, Inc.
Phase
Phase 1
Overall status
Recruiting
Start date
January 8, 2026
Completion date
October 31, 2028
Enrollment
574 (estimated)
Sites
9

Conditions

As the registry lists them; a condition with its own page is linked.

advanced solid tumors, colorectal cancer (crc), crc, lung cancer (nsclc), non-small cell lung cancer (nsclc), nsclc, pancreatic adenocarcinoma, pancreatic cancer, pancreatic ductal adenocarcinoma (pdac), pdac