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Clinical trial

A Phase 2, Open-label Study of VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, With and Without an Anti-EGFR Antibody, and With an Anti-EGFR Antibody and Chemotherapy, in Patients With Metastatic KRAS G12D-Mutated Colorectal Adenocarcinoma (TARGET-D 203)

NCT07659795 is registered in ClinicalTrials.gov with Verastem, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 2, Open-label Study of VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, With and Without an Anti-EGFR Antibody, and With an Anti-EGFR Antibody and Chemotherapy, in Patients With Metastatic KRAS G12D-Mutated Colorectal Adenocarcinoma (TARGET-D 203)
Lead sponsor
Verastem, Inc.
Phase
Phase 2
Overall status
Recruiting
Start date
July 28, 2026
Completion date
December 31, 2028
Enrollment
150 (estimated)
Sites
23

Conditions

As the registry lists them; a condition with its own page is linked.

colorectal cancer