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Clinical trial

A Phase 1/2, Open-label Study of VS-7375, a KRAS G12D (ON/OFF) Inhibitor, as Monotherapy and in Combination, in Patients With Advanced KRAS G12D-Mutated Solid Tumors

NCT07020221 is registered in ClinicalTrials.gov with Verastem, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1/2, Open-label Study of VS-7375, a KRAS G12D (ON/OFF) Inhibitor, as Monotherapy and in Combination, in Patients With Advanced KRAS G12D-Mutated Solid Tumors
Lead sponsor
Verastem, Inc.
Phase
Phase 1/2
Overall status
Recruiting
Start date
June 24, 2025
Completion date
December 31, 2028
Enrollment
295 (estimated)
Sites
14

Conditions

As the registry lists them; a condition with its own page is linked.

colorectal cancer, g12d mutated kras, non small cell lung cancer, pancreatic ductal adenocarcinoma, solid tumor, adult