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Clinical trial

Dynamic Adaptive Radiotherapy for Non-Small Cell Lung Cancer With Leptomeningeal Metastasis After Resistance to Third-Generation TKIs in the Consolidation Phase: A Multicenter Randomized Controlled Trial Comparing Outcomes Between Proton Craniospinal Irradiation and Intrathecal Pemetrexed (DART-LM)

NCT07751536 is registered in ClinicalTrials.gov with Shuanghu Yuan as lead sponsor.

NCT NCT07751536
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Registry record

As filed in ClinicalTrials.gov.

Title
Dynamic Adaptive Radiotherapy for Non-Small Cell Lung Cancer With Leptomeningeal Metastasis After Resistance to Third-Generation TKIs in the Consolidation Phase: A Multicenter Randomized Controlled Trial Comparing Outcomes Between Proton Craniospinal Irradiation and Intrathecal Pemetrexed (DART-LM)
Lead sponsor
Shuanghu Yuan
Phase
Not applicable
Overall status
Recruiting
Start date
August 5, 2026
Completion date
July 31, 2028
Enrollment
84 (estimated)
Sites
3

Conditions

As the registry lists them; a condition with its own page is linked.

leptomeningeal metastasis from lung cancer