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Clinical trial

Channeling Hope Trial 1: A Phase 1, Open-label, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) of Chronic Aprepitant Use in Individuals With Congenital Contractures of the Limbs and Face, Hypotonia, and Development Delay (CLIFAHDD)

NCT07845825 is registered in ClinicalTrials.gov with The University of Texas Health Science Center at San Antonio as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Channeling Hope Trial 1: A Phase 1, Open-label, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) of Chronic Aprepitant Use in Individuals With Congenital Contractures of the Limbs and Face, Hypotonia, and Development Delay (CLIFAHDD)
Lead sponsor
The University of Texas Health Science Center at San Antonio
Phase
Phase 1
Overall status
Recruiting
Start date
October 31, 2026
Completion date
July 31, 2027
Enrollment
5 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

ataxia - other, clifahdd, congenital contractures of the limbs and face, hypotonia, and developmental delay, nalcn channelopathy, neurodevelopmental disorder (diagnosis)