Condition (MeSH)
Acanthosis Nigricans
ClinicalTrials.gov lists 18 trials for Acanthosis Nigricans or a narrower condition beneath it. National Center for Research Resources (NCRR) has the most among industry and government lead sponsors, with 2.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
18 of the 18 trials are tagged with Acanthosis Nigricans itself; the rest are tagged with a narrower condition beneath it.
When did Acanthosis Nigricans trials start? (12)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 2 |
| 2024 | 2 |
| 2023 | 1 |
| 2022 | 2 |
| 2021 | 1 |
| 2017 | 2 |
| 2015 | 1 |
| 2014 | 1 |
| 2012 | 1 |
Showing 10 of 12 earlier years.
No forecast is made for this condition: it averages 1.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Acanthosis Nigricans trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 2 |
| Phase 4 | 1 |
| Not applicable | 7 |
| Observational | 5 |
How many Acanthosis Nigricans trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 1 |
| Completed | 11 |
| Unknown status | 5 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Acanthosis Nigricans trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Center for Research Resources (NCRR) | 2 |
| Jinnah Postgraduate Medical Centre | 1 |
Which drugs are being tested for Acanthosis Nigricans? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| .spironolactone | 1 |
| Chromium Picolinate | 1 |
Interventions as named in the registry (8)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| 1% Metformin | 4 |
| Topical metformin | 1 |
| Lupron / Leuprolide acetate | 1 |
| topical intervention | 1 |
| Sirolimus 0.2% | 1 |
Showing 5 of 8 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Acanthosis Nigricans trials report? (4)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Diabetic ketoacidosis | 2 | 1 |
| Appendicitis | 1 | 1 |
| Pneumonia | 1 | 1 |
| Severe hypoglycemia | 1 | 1 |
Which publications cover Acanthosis Nigricans? (23)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Maintenance Outcomes of the Children's Healthy Living Program on Overweight, Obesity, and Acanthosis Nigricans Among Young Children in the US-Affiliated Pacific Region: A Randomized Clinical Trial. | JAMA network open | 2022 | Yes |
| Determination of Child Waist Circumference Cut Points for Metabolic Risk Based on Acanthosis Nigricans, the Children's Healthy Living Program. | Preventing chronic disease | 2021 | Yes |
| Topical sirolimus therapy for epidermal nevus with features of acanthosis nigricans. | Pediatric dermatology | 2019 | Yes |
| Effect of the Children's Healthy Living Program on Young Child Overweight, Obesity, and Acanthosis Nigricans in the US-Affiliated Pacific Region: A Randomized Clinical Trial. | JAMA network open | 2018 | Yes |
| Prevalence of obesity and acanthosis nigricans among young children in the children's healthy living program in the United States Affiliated Pacific. | Medicine | 2016 | Yes |
Showing 5 of 23 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.