Condition (MeSH)
Transfusion-Related Acute Lung Injury
ClinicalTrials.gov lists 12 trials for Transfusion-Related Acute Lung Injury or a narrower condition beneath it.
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Trials per phase
12 of the 12 trials are tagged with Transfusion-Related Acute Lung Injury itself; the rest are tagged with a narrower condition beneath it.
When did Transfusion-Related Acute Lung Injury trials start? (9)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Phase 2
- Phase 3
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2020 | 1 |
| 2019 | 2 |
| 2016 | 2 |
| 2015 | 1 |
| 2012 | 1 |
| 2011 | 2 |
| 2009 | 1 |
| 2005 | 1 |
No forecast is made for this condition: it averages 0.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 12 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Transfusion-Related Acute Lung Injury trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 1 |
| Phase 2 | 2 |
| Phase 3 | 2 |
| Observational | 7 |
How many Transfusion-Related Acute Lung Injury trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Completed | 7 |
| Terminated | 3 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Transfusion-Related Acute Lung Injury trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Cerus Corporation | 1 |
| Tel-Aviv Sourasky Medical Center | 1 |
Which drugs are being tested for Transfusion-Related Acute Lung Injury? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Fibrinogen Concentrate | 1 |
| Prothrombin Complex Concentrate | 1 |
| Fresh Frozen Plasma | 1 |
Interventions as named in the registry (6)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Ascorbic Acid Injectable Product | 1 |
| Blood Transfusion | 1 |
| Standard of care red blood cell transfusion. | 1 |
| 1:1:1 Blood Transfusion Ratio | 1 |
| 1:1:2 Blood Transfusion Ratio | 1 |
Showing 5 of 6 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Transfusion-Related Acute Lung Injury trials report? (6)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Hypernatremia associated with hypertonic saline use | 5 | 1 |
| Hyperkalemia | 2 | 1 |
| Profound Anemia | 2 | 1 |
| hypoxemia | 2 | 1 |
| Acute respiratory failure | 1 | 1 |
Showing 5 of 6 adverse events.
Which publications cover Transfusion-Related Acute Lung Injury? (15)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Role of ascorbic acid infusion in critically ill patients with transfusion-related acute lung injury. | British journal of clinical pharmacology | 2022 | Yes |
| Frequency and timing of all-cause deaths in visits involving suspected transfusion reactions, and the significance of cardiopulmonary disturbances. | Vox sanguinis | 2021 | Yes |
| Transfusion-Associated Circulatory Overload and Transfusion-Related Acute Lung Injury. | American journal of clinical pathology | 2021 | Yes |
| Transfusion-associated circulatory overload and transfusion-related acute lung injury. | Blood | 2019 | Yes |
| A consensus redefinition of transfusion-related acute lung injury. | Transfusion | 2019 | Yes |
Showing 5 of 15 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.