Condition (MeSH)
Alkaptonuria
ClinicalTrials.gov lists 10 trials for Alkaptonuria or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
10 of the 10 trials are tagged with Alkaptonuria itself; the rest are tagged with a narrower condition beneath it.
When did Alkaptonuria trials start? (8)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 2/3
- Phase 3
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2024 | 1 |
| 2021 | 2 |
| 2019 | 2 |
| 2014 | 1 |
| 2013 | 1 |
| 2011 | 1 |
| 2005 | 1 |
| 2000 | 1 |
No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 10 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Alkaptonuria trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 2 |
| Phase 2/3 | 1 |
| Phase 3 | 1 |
| Not applicable | 3 |
| Observational | 3 |
How many Alkaptonuria trials are recruiting? (3)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 1 |
| Completed | 6 |
| Unknown status | 3 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Alkaptonuria trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Human Genome Research Institute (NHGRI) | 2 |
| Vitaflo International, Ltd | 2 |
| Liverpool University Hospitals NHS Foundation Trust | 1 |
| metaX Institut fuer Diatetik GmbH | 1 |
Which drugs are being tested for Alkaptonuria? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Nitisinone | 4 |
Which serious adverse events do Alkaptonuria trials report? (8)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| accidental overdose | 1 | 1 |
| anemia | 1 | 1 |
| atrial fibrillation | 1 | 1 |
| bile duct stone | 1 | 1 |
| keratitis | 1 | 1 |
Showing 5 of 8 adverse events.
Which publications cover Alkaptonuria? (11)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 11 publications.
Prevalence (24)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Alkaptonuria | Point prevalence | 1-9 / 1 000 000 | United States | US | Exact |
| Alkaptonuria | Point prevalence | 1-9 / 1 000 000 | United States | US | Unspecified |
| Alkaptonuria | Point prevalence | 1-9 / 1 000 000 | United States | US | Exact |
| Alkaptonuria | Prevalence at birth | 1-9 / 1 000 000 | United States | US | Unspecified |
| Alkaptonuria | Prevalence at birth | 1-9 / 1 000 000 | United States | US | Exact |
Showing 5 of 24 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Alkaptonuria | 56 | Exact | Orphadata Science knowledge files, Product 1 |
| Alkaptonuria | 56 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.