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Condition (MeSH)

Bacterial Infections

ClinicalTrials.gov lists 6,322 trials for Bacterial Infections or a narrower condition beneath it. GlaxoSmithKline has the most among industry and government lead sponsors, with 352.

MeSH D001424 Infections C01
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Phase 1 Phase 1 700 Phase 1/2 Phase 1/2 152 Phase 2 Phase 2 857 Phase 2/3 Phase 2/3 112 Phase 3 Phase 3 946 Phase 4 Phase 4 625 Not applicable Not applicable 1,212 Observational Observational 1,706 Phase 1 Phase 1 700 Phase 1/2 Phase 1/2 152 Phase 2 Phase 2 857 Phase 2/3 Phase 2/3 112 Phase 3 Phase 3 946 Phase 4 Phase 4 625 Not applicable Not applicable 1,212 Observational Observational 1,706

Trials per phase

2 more sections with rows

583 of the 6,322 trials are tagged with Bacterial Infections itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Bacterial Infections trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 16 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 368

1990: 1 trials (Phase 2 1) 1991: 4 trials (Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 1) 1992: 3 trials (Observational 1, Phase 3 1, Phase 2 1) 1993: 4 trials (Phase 3 3, Phase 2 1) 1994: 7 trials (Observational 1, Not applicable 1, Phase 4 4, Phase 2 1) 1995: 13 trials (Observational 7, Not applicable 1, Phase 3 3, Phase 2 1, Phase 1 1) 1996: 2 trials (Observational 1, Phase 4 1) 1997: 13 trials (Observational 2, Not applicable 1, Phase 4 2, Phase 3 6, Phase 2 1, Phase 1 1) 1998: 7 trials (Observational 2, Not applicable 1, Phase 3 1, Phase 2 2, Phase 1 1) 1999: 18 trials (Observational 3, Not applicable 2, Phase 3 4, Phase 2/3 1, Phase 2 7, Phase 1 1) 2000: 27 trials (Observational 6, Not applicable 6, Phase 4 2, Phase 3 9, Phase 2 3, Phase 1/2 1) 2001: 28 trials (Observational 4, Not applicable 1, Phase 4 9, Phase 3 8, Phase 2/3 1, Phase 2 4, Phase 1 1) 2002: 56 trials (Observational 11, Not applicable 4, Phase 4 9, Phase 3 16, Phase 2/3 1, Phase 2 7, Phase 1/2 2, Phase 1 6) 2003: 80 trials (Observational 8, Not applicable 9, Phase 4 15, Phase 3 18, Phase 2/3 2, Phase 2 18, Phase 1/2 2, Phase 1 8) 2004: 101 trials (Observational 16, Not applicable 11, Phase 4 17, Phase 3 24, Phase 2/3 4, Phase 2 14, Phase 1/2 5, Phase 1 10) 2005: 175 trials (Observational 46, Not applicable 16, Phase 4 15, Phase 3 47, Phase 2/3 2, Phase 2 30, Phase 1/2 1, Phase 1 18) 2006: 205 trials (Observational 46, Not applicable 19, Phase 4 28, Phase 3 68, Phase 2/3 2, Phase 2 23, Phase 1/2 4, Phase 1 15) 2007: 209 trials (Observational 38, Not applicable 31, Phase 4 29, Phase 3 60, Phase 2/3 4, Phase 2 20, Phase 1/2 2, Phase 1 25) 2008: 221 trials (Observational 55, Not applicable 19, Phase 4 30, Phase 3 47, Phase 2/3 1, Phase 2 38, Phase 1/2 6, Phase 1 25) 2009: 213 trials (Observational 54, Not applicable 41, Phase 4 12, Phase 3 37, Phase 2/3 5, Phase 2 31, Phase 1/2 5, Phase 1 28) 2010: 251 trials (Observational 52, Not applicable 30, Phase 4 31, Phase 3 41, Phase 2/3 5, Phase 2 54, Phase 1/2 6, Phase 1 32) 2011: 228 trials (Observational 58, Not applicable 31, Phase 4 30, Phase 3 43, Phase 2/3 2, Phase 2 37, Phase 1 27) 2012: 238 trials (Observational 64, Not applicable 36, Phase 4 35, Phase 3 40, Phase 2/3 6, Phase 2 26, Phase 1/2 4, Phase 1 27) 2013: 234 trials (Observational 47, Not applicable 46, Phase 4 23, Phase 3 37, Phase 2/3 3, Phase 2 33, Phase 1/2 7, Phase 1 38) 2014: 253 trials (Observational 61, Not applicable 44, Phase 4 23, Phase 3 49, Phase 2/3 9, Phase 2 37, Phase 1/2 6, Phase 1 24) 2015: 254 trials (Observational 69, Not applicable 60, Phase 4 20, Phase 3 30, Phase 2/3 3, Phase 2 36, Phase 1/2 6, Phase 1 30) 2016: 263 trials (Observational 76, Not applicable 49, Phase 4 29, Phase 3 27, Phase 2/3 3, Phase 2 33, Phase 1/2 5, Phase 1 41) 2017: 287 trials (Other 1, Observational 87, Not applicable 68, Phase 4 31, Phase 3 22, Phase 2/3 3, Phase 2 29, Phase 1/2 11, Phase 1 35) 2018: 280 trials (Observational 81, Not applicable 60, Phase 4 21, Phase 3 31, Phase 2/3 8, Phase 2 44, Phase 1/2 3, Phase 1 32) 2019: 368 trials (Observational 123, Not applicable 75, Phase 4 31, Phase 3 40, Phase 2/3 7, Phase 2 44, Phase 1/2 15, Phase 1 33) 2020: 283 trials (Observational 105, Not applicable 60, Phase 4 18, Phase 3 32, Phase 2/3 7, Phase 2 30, Phase 1/2 2, Phase 1 29) 2021: 339 trials (Observational 110, Not applicable 88, Phase 4 29, Phase 3 28, Phase 2/3 4, Phase 2 45, Phase 1/2 9, Phase 1 26) 2022: 314 trials (Other 1, Observational 97, Not applicable 59, Phase 4 29, Phase 3 33, Phase 2/3 6, Phase 2 41, Phase 1/2 12, Phase 1 36) 2023: 310 trials (Observational 92, Not applicable 80, Phase 4 26, Phase 3 28, Phase 2/3 5, Phase 2 33, Phase 1/2 8, Phase 1 38) 2024: 332 trials (Observational 100, Not applicable 89, Phase 4 18, Phase 3 37, Phase 2/3 6, Phase 2 35, Phase 1/2 15, Phase 1 32) 2025: 278 trials (Observational 84, Not applicable 57, Phase 4 27, Phase 3 28, Phase 2/3 7, Phase 2 33, Phase 1/2 6, Phase 1 36)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 317
2025 278
2024 332
2023 310
2022 314
2021 339
2020 283
2019 368
2018 280
2017 287

Forecast of the full-year count, planned starts included, not rows of this table: about 350 trials starting in 2026 and about 310 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 425 trials still running at the 2026-10-09 snapshot; registered median of 18 months across 4,176 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Bacterial Infections trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 700
Phase 1/2 152
Phase 2 857
Phase 2/3 112
Phase 3 946
Phase 4 625
Not applicable 1,212
Observational 1,706
Expanded access 10
Unknown 2

How many Bacterial Infections trials are recruiting? (12)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 248
Recruiting 560
Enrolling by invitation 31
Active, not recruiting 175
Available 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Bacterial Infections trials? (9)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
GlaxoSmithKline 352
National Institute of Allergy and Infectious Diseases (NIAID) 233
Pfizer 135
Sanofi Pasteur, a Sanofi Company 127
Merck Sharp & Dohme LLC 80

Which drugs are being tested for Bacterial Infections? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Bedaquiline 61

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Isoniazida 104
Rifampicin 94
1% Azithromycin 93
Vancomycin 1.1% 91
Zyvox - linezolid 81

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Bacterial Infections trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 2,868 318
Gastroenteritis 2,460 199
Preterm delivery 2,457 1
Small for gestational age 2,457 1
Bronchiolitis 2,293 125

Which publications cover Bacterial Infections? (1,786)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (11)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages