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Condition (MeSH)

Body Weight

ClinicalTrials.gov lists 15,131 trials for Body Weight or a narrower condition beneath it. Novo Nordisk A/S has the most among industry and government lead sponsors, with 200.

MeSH D001835 Pathological Conditions, Signs and Symptoms C23
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Phase 1 Phase 1 808 Phase 1/2 Phase 1/2 163 Phase 2 Phase 2 759 Phase 2/3 Phase 2/3 143 Phase 3 Phase 3 608 Phase 4 Phase 4 655 Not applicable Not applicable 8,926 Observational Observational 3,062 Phase 1 Phase 1 808 Phase 1/2 Phase 1/2 163 Phase 2 Phase 2 759 Phase 2/3 Phase 2/3 143 Phase 3 Phase 3 608 Phase 4 Phase 4 655 Not applicable Not applicable 8,926 Observational Observational 3,062

Trials per phase (log scale)

2 more sections with rows

649 of the 15,131 trials are tagged with Body Weight itself; the rest are tagged with a narrower condition beneath it.

Get the Body Weight report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Body Weight trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 41 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 979

1990: 4 trials (Observational 4) 1991: 4 trials (Observational 4) 1992: 4 trials (Observational 3, Phase 3 1) 1993: 6 trials (Observational 4, Not applicable 1, Phase 2 1) 1994: 2 trials (Observational 1, Phase 1/2 1) 1995: 8 trials (Observational 6, Not applicable 1, Phase 3 1) 1996: 10 trials (Observational 6, Not applicable 2, Phase 4 1, Phase 3 1) 1997: 8 trials (Observational 2, Not applicable 4, Phase 2 1, Phase 1/2 1) 1998: 23 trials (Observational 9, Not applicable 4, Phase 4 1, Phase 3 4, Phase 2 5) 1999: 31 trials (Observational 13, Not applicable 9, Phase 4 1, Phase 3 3, Phase 2/3 1, Phase 2 2, Phase 1/2 2) 2000: 50 trials (Observational 11, Not applicable 15, Phase 4 4, Phase 3 11, Phase 2 6, Phase 1 3) 2001: 57 trials (Observational 18, Not applicable 22, Phase 4 3, Phase 3 9, Phase 2 4, Phase 1 1) 2002: 71 trials (Observational 8, Not applicable 41, Phase 4 3, Phase 3 8, Phase 2/3 1, Phase 2 5, Phase 1/2 2, Phase 1 3) 2003: 111 trials (Observational 20, Not applicable 37, Phase 4 13, Phase 3 11, Phase 2/3 6, Phase 2 14, Phase 1/2 6, Phase 1 4) 2004: 187 trials (Observational 31, Not applicable 85, Phase 4 17, Phase 3 18, Phase 2/3 3, Phase 2 22, Phase 1/2 5, Phase 1 6) 2005: 241 trials (Observational 53, Not applicable 101, Phase 4 18, Phase 3 15, Phase 2/3 8, Phase 2 24, Phase 1/2 6, Phase 1 16) 2006: 288 trials (Observational 50, Not applicable 134, Phase 4 22, Phase 3 30, Phase 2/3 4, Phase 2 23, Phase 1/2 5, Phase 1 20) 2007: 386 trials (Observational 82, Not applicable 194, Phase 4 19, Phase 3 29, Phase 2/3 4, Phase 2 35, Phase 1/2 7, Phase 1 16) 2008: 439 trials (Observational 105, Not applicable 208, Phase 4 22, Phase 3 21, Phase 2/3 7, Phase 2 41, Phase 1/2 5, Phase 1 30) 2009: 483 trials (Observational 120, Not applicable 244, Phase 4 28, Phase 3 16, Phase 2/3 11, Phase 2 29, Phase 1/2 4, Phase 1 31) 2010: 521 trials (Observational 111, Not applicable 301, Phase 4 29, Phase 3 14, Phase 2/3 13, Phase 2 19, Phase 1/2 5, Phase 1 29) 2011: 543 trials (Observational 119, Not applicable 312, Phase 4 28, Phase 3 30, Phase 2/3 3, Phase 2 22, Phase 1/2 6, Phase 1 23) 2012: 603 trials (Observational 122, Not applicable 372, Phase 4 31, Phase 3 22, Phase 2/3 5, Phase 2 27, Phase 1/2 2, Phase 1 22) 2013: 581 trials (Observational 109, Not applicable 359, Phase 4 28, Phase 3 17, Phase 2/3 4, Phase 2 26, Phase 1/2 11, Phase 1 27) 2014: 613 trials (Observational 112, Not applicable 393, Phase 4 31, Phase 3 14, Phase 2/3 11, Phase 2 22, Phase 1/2 6, Phase 1 24) 2015: 655 trials (Observational 116, Not applicable 451, Phase 4 26, Phase 3 10, Phase 2/3 3, Phase 2 26, Phase 1/2 6, Phase 1 17) 2016: 781 trials (Other 1, Observational 190, Not applicable 480, Phase 4 33, Phase 3 18, Phase 2/3 8, Phase 2 19, Phase 1/2 5, Phase 1 27) 2017: 735 trials (Other 1, Observational 145, Not applicable 483, Phase 4 31, Phase 3 12, Phase 2/3 4, Phase 2 33, Phase 1/2 6, Phase 1 20) 2018: 751 trials (Observational 144, Not applicable 507, Phase 4 25, Phase 3 16, Phase 2/3 3, Phase 2 20, Phase 1/2 8, Phase 1 28) 2019: 764 trials (Observational 161, Not applicable 516, Phase 4 30, Phase 3 15, Phase 2/3 6, Phase 2 11, Phase 1/2 3, Phase 1 22) 2020: 625 trials (Other 1, Observational 155, Not applicable 388, Phase 4 20, Phase 3 8, Phase 2/3 2, Phase 2 13, Phase 1/2 5, Phase 1 33) 2021: 778 trials (Observational 144, Not applicable 523, Phase 4 20, Phase 3 22, Phase 2/3 4, Phase 2 32, Phase 1/2 4, Phase 1 29) 2022: 843 trials (Observational 192, Not applicable 531, Phase 4 22, Phase 3 22, Phase 2/3 10, Phase 2 24, Phase 1/2 5, Phase 1 37) 2023: 929 trials (Other 1, Observational 166, Not applicable 597, Phase 4 34, Phase 3 34, Phase 2/3 8, Phase 2 36, Phase 1/2 12, Phase 1 41) 2024: 926 trials (Observational 162, Not applicable 552, Phase 4 25, Phase 3 28, Phase 2/3 4, Phase 2 58, Phase 1/2 14, Phase 1 83) 2025: 979 trials (Observational 172, Not applicable 526, Phase 4 39, Phase 3 52, Phase 2/3 5, Phase 2 76, Phase 1/2 13, Phase 1 96)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 957
2025 979
2024 926
2023 929
2022 843
2021 778
2020 625
2019 764
2018 751
2017 735

Forecast of the full-year count, planned starts included, not rows of this table: about 1,200 trials starting in 2026 and about 1,000 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 1,369 trials still running at the 2026-10-09 snapshot; registered median of 19 months across 10,052 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Body Weight trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 808
Phase 1/2 163
Phase 2 759
Phase 2/3 143
Phase 3 608
Phase 4 655
Not applicable 8,926
Observational 3,062
Expanded access 3
Unknown 4

How many Body Weight trials are recruiting? (12)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 634
Recruiting 1,524
Enrolling by invitation 125
Active, not recruiting 672
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Body Weight trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Novo Nordisk A/S 200
Eli Lilly and Company 114
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 107

Which drugs are being tested for Body Weight? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Semaglutide 184
TIRZEPATIDE 134
LIRAGLUTIDE 107
Exenatide 38
Maltodextrin 34

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Exercise 167
1% Metformin 124
Diet 86
Control (placebo) group 85
Weight loss 58

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Body Weight trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Major Adverse Cardiovascular Events 6,762 1
Major Adverse Kidney Events 5,557 1
Any SAE Report 2,676 1
Acute myocardial infarction 992 37
Atrial fibrillation 940 54

Which publications cover Body Weight? (6,407)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (5)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages