Condition (MeSH)
Intracranial Arteriovenous Malformations
ClinicalTrials.gov lists 47 trials for Intracranial Arteriovenous Malformations or a narrower condition beneath it. Fondation Ophtalmologique Adolphe de Rothschild has the most among industry and government lead sponsors, with 2.
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Trials per phase (log scale)
43 of the 47 trials are tagged with Intracranial Arteriovenous Malformations itself; the rest are tagged with a narrower condition beneath it.
When did Intracranial Arteriovenous Malformations trials start? (19)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 3
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 4 |
| 2025 | 4 |
| 2024 | 3 |
| 2023 | 1 |
| 2022 | 4 |
| 2021 | 5 |
| 2020 | 2 |
| 2019 | 4 |
| 2018 | 3 |
| 2017 | 2 |
Showing 10 of 19 earlier years.
No forecast is made for this condition: it averages 3.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 35 months across 21 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Intracranial Arteriovenous Malformations trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 2/3 | 1 |
| Phase 3 | 2 |
| Not applicable | 15 |
| Observational | 26 |
How many Intracranial Arteriovenous Malformations trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 4 |
| Recruiting | 11 |
| Active, not recruiting | 2 |
| Completed | 18 |
| Terminated | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Intracranial Arteriovenous Malformations trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Fondation Ophtalmologique Adolphe de Rothschild | 2 |
| Balt Extrusion | 1 |
| Basecamp Vascular | 1 |
Which drugs are being tested for Intracranial Arteriovenous Malformations? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Lovastatin | 1 |
Interventions as named in the registry (5)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Single in situ intra-arterial injection of bevacizumab | 1 |
| Indocyanine Green dye | 1 |
| Medical Management | 1 |
| Embolization Therapy | 1 |
| Bevacizumab 1 | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Intracranial Arteriovenous Malformations trials report? (2)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Complete chorion-amnion separation | 1 | 1 |
| Sinus tachycardia, hypotension | 1 | 1 |
Which publications cover Intracranial Arteriovenous Malformations? (138)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 138 publications.
Prevalence (3)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Brain arteriovenous malformation, nidus type | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Exact |
| Brain arteriovenous malformation, nidus type | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Exact |
| Brain arteriovenous malformation, nidus type | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Unspecified |
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Brain arteriovenous malformation, nidus type | 46724 | Exact | Orphadata Science knowledge files, Product 1 |
| Brain arteriovenous malformation, nidus type | 46724 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.