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Condition (MeSH)

Croup

ClinicalTrials.gov lists 18 trials for Croup or a narrower condition beneath it. ResApp Health Limited has the most among industry and government lead sponsors, with 3.

MeSH D003440 Respiratory Tract Diseases C08 C09
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Phase 2 Phase 2 1 Phase 3 Phase 3 6 Phase 4 Phase 4 3 Not applicable Not applicable 3 Observational Observational 5 Phase 2 Phase 2 1 Phase 3 Phase 3 6 Phase 4 Phase 4 3 Not applicable Not applicable 3 Observational Observational 5

Trials per phase

18 of the 18 trials are tagged with Croup itself; the rest are tagged with a narrower condition beneath it.

Get the Croup report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Croup trials start? (11)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 5

1999: 1 trials (Phase 3 1) 2000: 1 trials (Not applicable 1) 2001: 1 trials (Phase 2 1) 2009: 1 trials (Phase 4 1) 2010: 1 trials (Phase 3 1) 2012: 1 trials (Phase 3 1) 2014: 1 trials (Observational 1) 2016: 3 trials (Observational 1, Not applicable 1, Phase 4 1) 2018: 2 trials (Observational 1, Phase 4 1) 2019: 1 trials (Observational 1) 2024: 5 trials (Observational 1, Not applicable 1, Phase 3 3)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2024 5
2019 1
2018 2
2016 3
2014 1
2012 1
2010 1
2009 1
2001 1
2000 1

No forecast is made for this condition: it averages 1.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Croup trials in? (5)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 2 1
Phase 3 6
Phase 4 3
Not applicable 3
Observational 5

How many Croup trials are recruiting? (4)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 2
Completed 10
Terminated 4
Unknown status 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Croup trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
ResApp Health Limited 3
Bitop AG 1
Canadian Institutes of Health Research (CIHR) 1
Chiesi Farmaceutici S.p.A. 1

Which drugs are being tested for Croup? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Olive Oil 1
PREDNISOLONE 1
OPN-375 1
Prednisone 1

Interventions as named in the registry (6)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Dexamethasone/Dexamethasone acetate 4
Dexamethasone IV for PO 1
Low-dose epinephrine 1
intramuscular dexamethasone 1
beclomethasone dipropionate suspension for nebulisation 800 mcg/2 ml 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Croup? (35)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Fish Oil and Vitamin D Supplementations in Pregnancy Protect Against Childhood Croup. The journal of allergy and clinical immunology. In practice 2023 Yes
Outdoor Cold Air Versus Room Temperature Exposure for Croup Symptoms: A Randomized Controlled Trial. Pediatrics 2023 Yes
COVID-19-Associated Croup in Children. Pediatrics 2022 Yes
Croup Associated With SARS-CoV-2: Pediatric Laryngotracheitis During the Omicron Surge. Journal of the Pediatric Infectious Diseases Society 2022 Yes
Automatic Croup Diagnosis Using Cough Sound Recognition. IEEE transactions on bio-medical engineering 2019 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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