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Condition (MeSH)

Dysplastic Nevus Syndrome

ClinicalTrials.gov lists 23 trials for Dysplastic Nevus Syndrome or a narrower condition beneath it. Orlucent, Inc has the most among industry and government lead sponsors, with 3.

MeSH D004416 Neoplasms Neoplasm C04 C16
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Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Phase 3 Phase 3 1 Not applicable Not applicable 3 Observational Observational 16 Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Phase 3 Phase 3 1 Not applicable Not applicable 3 Observational Observational 16

Trials per phase

23 of the 23 trials are tagged with Dysplastic Nevus Syndrome itself; the rest are tagged with a narrower condition beneath it.

Get the Dysplastic Nevus Syndrome report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Dysplastic Nevus Syndrome trials start? (17)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Not applicable
  • Observational

Top of scale: 2

1999: 1 trials (Observational 1) 2001: 1 trials (Observational 1) 2002: 1 trials (Observational 1) 2006: 1 trials (Phase 1/2 1) 2007: 1 trials (Phase 2 1) 2008: 1 trials (Observational 1) 2012: 1 trials (Phase 1 1) 2013: 2 trials (Observational 2) 2014: 2 trials (Observational 1, Phase 3 1) 2016: 1 trials (Observational 1) 2017: 1 trials (Observational 1) 2018: 2 trials (Observational 1, Not applicable 1) 2019: 2 trials (Observational 2) 2020: 2 trials (Observational 1, Not applicable 1) 2022: 1 trials (Observational 1) 2023: 2 trials (Observational 1, Not applicable 1) 2025: 1 trials (Observational 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 1
2023 2
2022 1
2020 2
2019 2
2018 2
2017 1
2016 1
2014 2
2013 2

No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Dysplastic Nevus Syndrome trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 1/2 1
Phase 2 1
Phase 3 1
Not applicable 3
Observational 16

How many Dysplastic Nevus Syndrome trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 6
Active, not recruiting 1
Completed 11
Terminated 1
Withdrawn 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Dysplastic Nevus Syndrome trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Orlucent, Inc 3
National Cancer Institute (NCI) 2
Immunovia, Inc. 1

Interventions as named in the registry (8)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
B (CANA/MET IR FDC tablet - fed state) / A (CANA/MET IR FDC tablet - fasting state) 1
Single agent, adjuvant anti-PD1 therapy 1
data collection 1
Secretin 1
20% betulinic acid ointment 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Dysplastic Nevus Syndrome? (16)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Dysplastic/Clark naevus in the era of molecular pathology. The Australasian journal of dermatology 2019 Yes
Risks of Melanoma and Other Cancers in Melanoma-Prone Families over 4 Decades. The Journal of investigative dermatology 2018 Yes
A prospective study evaluating the utility of a 2-mm biopsy margin for complete removal of histologically atypical (dysplastic) nevi. Journal of the American Academy of Dermatology 2017 Yes
Association of genetic variants in CDK6 and XRCC1 with the risk of dysplastic nevi in melanoma-prone families. The Journal of investigative dermatology 2014 Yes
Dysplastic nevi and melanoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2013 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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