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Condition (MeSH)

Encephalitis, Arbovirus

ClinicalTrials.gov lists 146 trials for Encephalitis, Arbovirus or a narrower condition beneath it. Pfizer has the most among industry and government lead sponsors, with 19.

MeSH D004671 Infections C01 C10
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Phase 1 Phase 1 14 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 32 Phase 2/3 Phase 2/3 3 Phase 3 Phase 3 39 Phase 4 Phase 4 31 Not applicable Not applicable 5 Observational Observational 20 Phase 1 Phase 1 14 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 32 Phase 2/3 Phase 2/3 3 Phase 3 Phase 3 39 Phase 4 Phase 4 31 Not applicable Not applicable 5 Observational Observational 20

Trials per phase (log scale)

1 more section with rows

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When did Encephalitis, Arbovirus trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 20

1998: 1 trials (Phase 2/3 1) 2001: 2 trials (Phase 3 1, Phase 2 1) 2002: 6 trials (Phase 3 2, Phase 2 4) 2003: 1 trials (Phase 2 1) 2004: 5 trials (Phase 4 2, Phase 2 2, Phase 1 1) 2005: 20 trials (Observational 2, Phase 4 3, Phase 3 8, Phase 2 3, Phase 1 4) 2006: 5 trials (Phase 4 1, Phase 3 3, Phase 1 1) 2007: 10 trials (Observational 1, Phase 4 4, Phase 3 2, Phase 2 3) 2008: 10 trials (Phase 4 1, Phase 3 3, Phase 2 5, Phase 1 1) 2009: 9 trials (Observational 1, Phase 4 2, Phase 3 3, Phase 2 3) 2010: 9 trials (Observational 1, Phase 4 1, Phase 3 7) 2011: 4 trials (Observational 1, Phase 3 2, Phase 2/3 1) 2012: 7 trials (Phase 4 5, Phase 3 1, Phase 1 1) 2013: 7 trials (Not applicable 1, Phase 4 3, Phase 3 1, Phase 2 1, Phase 1 1) 2014: 6 trials (Observational 2, Not applicable 2, Phase 3 1, Phase 2 1) 2015: 9 trials (Phase 4 4, Phase 3 2, Phase 2/3 1, Phase 2 2) 2016: 2 trials (Observational 1, Phase 4 1) 2017: 2 trials (Phase 3 1, Phase 2 1) 2018: 1 trials (Phase 1 1) 2019: 3 trials (Observational 1, Phase 1 2) 2020: 2 trials (Observational 2) 2021: 4 trials (Not applicable 1, Phase 4 1, Phase 3 1, Phase 2 1) 2022: 3 trials (Observational 2, Phase 2 1) 2023: 2 trials (Observational 2) 2024: 7 trials (Observational 2, Phase 4 3, Phase 3 1, Phase 2 1) 2025: 7 trials (Observational 2, Not applicable 1, Phase 2 2, Phase 1/2 1, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 7
2024 7
2023 2
2022 3
2021 4
2020 2
2019 3
2018 1
2017 2

No forecast is made for this condition: it averages 4.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 17 months across 93 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Encephalitis, Arbovirus trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 14
Phase 1/2 1
Phase 2 32
Phase 2/3 3
Phase 3 39
Phase 4 31
Not applicable 5
Observational 20
Expanded access 1

How many Encephalitis, Arbovirus trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 5
Recruiting 6
Active, not recruiting 3
Completed 104
Terminated 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Encephalitis, Arbovirus trials? (11)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Pfizer 19
Valneva Austria GmbH 15
Sanofi Pasteur, a Sanofi Company 13
National Institute of Allergy and Infectious Diseases (NIAID) 7
Sanofi 7

Which drugs are being tested for Encephalitis, Arbovirus? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
IC51 16
Yellow Fever Vaccine 3

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Tick-Borne Encephalitis (TBE) Vaccine (Inactivated) 13
IMOJEV 4
Japanese Encephalitis purified inactivated vaccine 3
JEVAX 3
Symptomatic therapy 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Encephalitis, Arbovirus trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Gastroenteritis 101 13
Pneumonia 75 12
Febrile convulsion 59 10
Bronchitis 39 7
Viral infection 22 5

Which publications cover Encephalitis, Arbovirus? (3)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Flavivirus encephalitis. The New England journal of medicine 2004 Yes
Pathogenesis of flavivirus encephalitis. Advances in virus research 2003 Yes
Rural epidemic encephalitis in Venezuela caused by a group A arbovirus (VEE). Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progres en virologie medicale 1967 Yes

Sub-conditions in MeSH (4)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

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