Condition (MeSH)
West Nile Fever
ClinicalTrials.gov lists 12 trials for West Nile Fever or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 4.
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Trials per phase
12 of the 12 trials are tagged with West Nile Fever itself; the rest are tagged with a narrower condition beneath it.
When did West Nile Fever trials start? (8)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2024 | 1 |
| 2020 | 1 |
| 2009 | 1 |
| 2008 | 2 |
| 2006 | 1 |
| 2005 | 3 |
| 2004 | 1 |
No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are West Nile Fever trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 5 |
| Observational | 1 |
| Expanded access | 1 |
How many West Nile Fever trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 1 |
| Completed | 6 |
| Terminated | 2 |
| Withdrawn | 1 |
| No longer available | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most West Nile Fever trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | 4 |
| MacroGenics | 2 |
| Sanofi Pasteur, a Sanofi Company | 2 |
| Gili Regev-Yochay MD | 1 |
| Sarepta Therapeutics, Inc. | 1 |
Showing 5 of 6 sponsors.
Which drugs are being tested for West Nile Fever? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Fresh Frozen Plasma | 1 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| MGAWN1 | 2 |
| VRC-WNVDNA020-00-VP | 1 |
| WN/DEN4delta30 vaccine | 1 |
| AVI-4020 Injection | 1 |
| 0.9 % NaCl solution | 1 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do West Nile Fever trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Atrial fibrillation | 2 | 1 |
| Influenza | 2 | 1 |
| Abdominal hernia obstructive | 1 | 1 |
| Accidential poisoning | 1 | 1 |
| Angina pectoris | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover West Nile Fever? (56)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Clinical, Prognostic, and Longitudinal Functional and Neuropsychological Features of West Nile Virus Neuroinvasive Disease in the United States: A Systematic Review and Meta-Analysis. | Annals of neurology | 2025 | Yes |
| Contribution of climate change to the spatial expansion of West Nile virus in Europe. | Nature communications | 2024 | Yes |
| Neuroinvasive West Nile Virus Infection in Immunosuppressed and Immunocompetent Adults. | JAMA network open | 2024 | Yes |
| Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients. | The Journal of experimental medicine | 2023 | Yes |
| ASSESSING THE HUMORAL RESPONSE TO AND SAFETY OF A COMMERCIALLY AVAILABLE EQUINE WEST NILE VIRUS VACCINE IN A ZOO-BASED CONSERVATION BREEDING POPULATION OF ENDANGERED GREATER SAGE-GROUSE (<i>CENTROCERCUS UROPHASIANUS</i>). | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians | 2021 | Yes |
Showing 5 of 56 publications.
Prevalence (18)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| West-Nile encephalitis | Point prevalence | 1-9 / 1 000 000 | United States | US | Exact |
| West-Nile encephalitis | Point prevalence | 1-9 / 1 000 000 | United States | US | Exact |
| West-Nile encephalitis | Annual incidence | <1 / 1 000 000 | Austria | Not stated | Exact |
| West-Nile encephalitis | Annual incidence | <1 / 1 000 000 | Italy | Not stated | Exact |
| West-Nile encephalitis | Annual incidence | <1 / 1 000 000 | Austria | Not stated | Exact |
Showing 5 of 18 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| West-Nile encephalitis | 83476 | Exact | Orphadata Science knowledge files, Product 1 |
| West-Nile encephalitis | 83476 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.