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Condition (MeSH)

Foot Diseases

ClinicalTrials.gov lists 575 trials for Foot Diseases or a narrower condition beneath it.

MeSH D005534 Musculoskeletal Diseases C05 C17
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Phase 1 Phase 1 28 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 54 Phase 2/3 Phase 2/3 7 Phase 3 Phase 3 39 Phase 4 Phase 4 39 Not applicable Not applicable 326 Observational Observational 76 Phase 1 Phase 1 28 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 54 Phase 2/3 Phase 2/3 7 Phase 3 Phase 3 39 Phase 4 Phase 4 39 Not applicable Not applicable 326 Observational Observational 76

Trials per phase (log scale)

1 more section with rows

43 of the 575 trials are tagged with Foot Diseases itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Foot Diseases trials start? (28)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 55

1998: 1 trials (Phase 1 1) 1999: 1 trials (Observational 1) 2000: 2 trials (Phase 3 1, Phase 2 1) 2002: 2 trials (Observational 1, Phase 4 1) 2003: 4 trials (Not applicable 1, Phase 3 2, Phase 1 1) 2004: 4 trials (Not applicable 2, Phase 4 1, Phase 2 1) 2005: 12 trials (Observational 1, Not applicable 3, Phase 4 2, Phase 2/3 1, Phase 2 3, Phase 1 2) 2006: 7 trials (Phase 3 3, Phase 2 3, Phase 1/2 1) 2007: 10 trials (Not applicable 3, Phase 4 2, Phase 3 3, Phase 2 1, Phase 1 1) 2008: 11 trials (Observational 1, Not applicable 4, Phase 3 1, Phase 2 3, Phase 1 2) 2009: 13 trials (Observational 2, Not applicable 2, Phase 4 2, Phase 3 2, Phase 2/3 1, Phase 2 4) 2010: 18 trials (Observational 5, Not applicable 7, Phase 4 1, Phase 3 2, Phase 2 2, Phase 1 1) 2011: 29 trials (Observational 1, Not applicable 6, Phase 4 6, Phase 3 11, Phase 2/3 1, Phase 2 1, Phase 1 3) 2012: 19 trials (Observational 4, Not applicable 6, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 3, Phase 1 3) 2013: 15 trials (Observational 2, Not applicable 9, Phase 4 1, Phase 2/3 1, Phase 2 1, Phase 1 1) 2014: 30 trials (Observational 4, Not applicable 16, Phase 4 3, Phase 2 2, Phase 1/2 1, Phase 1 4) 2015: 21 trials (Observational 1, Not applicable 11, Phase 4 4, Phase 3 1, Phase 2/3 1, Phase 2 2, Phase 1/2 1) 2016: 21 trials (Not applicable 12, Phase 4 2, Phase 3 2, Phase 2 4, Phase 1 1) 2017: 24 trials (Observational 4, Not applicable 15, Phase 3 2, Phase 2 3) 2018: 17 trials (Observational 2, Not applicable 11, Phase 3 3, Phase 2 1) 2019: 32 trials (Observational 3, Not applicable 22, Phase 4 1, Phase 3 1, Phase 2 4, Phase 1/2 1) 2020: 23 trials (Observational 4, Not applicable 16, Phase 1/2 1, Phase 1 2) 2021: 30 trials (Observational 7, Not applicable 21, Phase 4 1, Phase 2 1) 2022: 40 trials (Observational 6, Not applicable 26, Phase 4 2, Phase 3 1, Phase 2/3 1, Phase 2 3, Phase 1 1) 2023: 45 trials (Observational 7, Not applicable 31, Phase 4 2, Phase 3 2, Phase 2 2, Phase 1 1) 2024: 45 trials (Observational 5, Not applicable 34, Phase 4 2, Phase 2 3, Phase 1 1) 2025: 55 trials (Observational 8, Not applicable 37, Phase 4 5, Phase 3 1, Phase 2 2, Phase 1 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 42
2025 55
2024 45
2023 45
2022 40
2021 30
2020 23
2019 32
2018 17
2017 24

Forecast of the full-year count, planned starts included, not rows of this table: about 55 trials starting in 2026 and about 55 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 28 months from start to primary completion across 47 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 361 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Foot Diseases trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 28
Phase 1/2 5
Phase 2 54
Phase 2/3 7
Phase 3 39
Phase 4 39
Not applicable 326
Observational 76
Expanded access 1

How many Foot Diseases trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 35
Recruiting 67
Enrolling by invitation 7
Active, not recruiting 8
Completed 329

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Foot Diseases trials? (7)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
MiMedx Group, Inc. 8
Sun Pharmaceutical Industries, Inc. 8
Pfizer 5
Endo USA Inc., a Keenova Therapeutics Company 4
Galderma R&D 4

Which drugs are being tested for Foot Diseases? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Corticosteroid 8
TERBINAFINE HYDROCHLORIDE (1%) 6

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
[PRP] platelet rich plasma 10
Dexamethasone/Dexamethasone acetate 6
Ketoconazole 2% 4
NaCl 0.9% NS 3
Vehicle Foam 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Foot Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Infection 27 2
Osteomyelitis 26 2
osteomyelitis 23 1
diabetic foot infection 14 1
cellulitis 13 1

Which publications cover Foot Diseases? (187)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (7)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages