Condition (MeSH)
Fractures, Open
ClinicalTrials.gov lists 43 trials for Fractures, Open or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
43 of the 43 trials are tagged with Fractures, Open itself; the rest are tagged with a narrower condition beneath it.
When did Fractures, Open trials start? (17)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 3 |
| 2024 | 3 |
| 2023 | 3 |
| 2022 | 2 |
| 2021 | 6 |
| 2020 | 5 |
| 2019 | 1 |
| 2018 | 4 |
| 2017 | 2 |
| 2016 | 2 |
Showing 10 of 17 earlier years.
No forecast is made for this condition: it averages 2.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Fractures, Open trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2/3 | 1 |
| Phase 3 | 4 |
| Phase 4 | 13 |
| Not applicable | 14 |
| Observational | 11 |
How many Fractures, Open trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 4 |
| Recruiting | 5 |
| Enrolling by invitation | 1 |
| Completed | 18 |
| Terminated | 8 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Fractures, Open trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| BONESUPPORT AB | 1 |
| LifeNet Health | 1 |
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Vancomycin 1.1% | 4 |
| tobramycin / TOBI | 3 |
| NaCl 0.9% NS | 1 |
| silversulfadiazine | 1 |
| Immunofluorescence Imaging | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Fractures, Open trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Study Fracture Related Complication | 1,462 | 2 |
| Other | 1,154 | 2 |
| Pulmonary | 284 | 2 |
| Renal | 221 | 2 |
| Cardiac | 216 | 2 |
Showing 5 of 10 adverse events.
Which publications cover Fractures, Open? (172)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Use of antibiotic-cement coated plate in the treatment of Gustilo-Anderson type III long bone fractures in low- and middle-income countries vs external fixation: A multicentre randomized control trial study protocol. | Injury | 2024 | Yes |
| Quality of Life after Open Extremity Trauma (QUINTET) study: An international, multicentric, observational, cohort study of quality of life following lower extremity open fractures. | Journal of plastic, reconstructive & aesthetic surgery : JPRAS | 2024 | Yes |
| Management of Hardware-Exposed Soft Tissue Defects Using Dermal Substitutes and Negative Pressure Wound Therapy. | Annals of plastic surgery | 2023 | Yes |
| Water for wound cleansing. | The Cochrane database of systematic reviews | 2022 | Yes |
| Management of soft-tissue coverage of open tibia fractures in Latin America: Techniques, timing, and resources. | Injury | 2022 | Yes |
Showing 5 of 172 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.