Condition (MeSH)
Hyaline Membrane Disease
ClinicalTrials.gov lists 25 trials for Hyaline Membrane Disease or a narrower condition beneath it. CENTOGENE GmbH Rostock has the most among industry and government lead sponsors, with 1.
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Trials per phase
25 of the 25 trials are tagged with Hyaline Membrane Disease itself; the rest are tagged with a narrower condition beneath it.
When did Hyaline Membrane Disease trials start? (15)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 6 |
| 2025 | 3 |
| 2022 | 2 |
| 2020 | 1 |
| 2019 | 1 |
| 2018 | 1 |
| 2017 | 1 |
| 2015 | 1 |
| 2014 | 1 |
| 2012 | 2 |
Showing 10 of 15 earlier years.
No forecast is made for this condition: it averages 2.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 25 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Hyaline Membrane Disease trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 3 |
| Phase 4 | 1 |
| Not applicable | 10 |
| Observational | 9 |
How many Hyaline Membrane Disease trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 7 |
| Recruiting | 3 |
| Completed | 10 |
| Terminated | 2 |
| Withdrawn | 2 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Hyaline Membrane Disease trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| CENTOGENE GmbH Rostock | 1 |
Which drugs are being tested for Hyaline Membrane Disease? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Calcium-vitamin D3 | 1 |
| Betamethasone | 1 |
| Poractant Alfa | 1 |
| Beclomethasone | 1 |
Interventions as named in the registry (5)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| nCPAP | 2 |
| Convalesscent Plasma | 1 |
| Oral Zinc | 1 |
| Dexamethasone/Dexamethasone acetate | 1 |
| Beta Carotene | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Hyaline Membrane Disease? (22)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Risk Factors of Respiratory Diseases Among Neonates in Neonatal Intensive Care Unit of Qena University Hospital, Egypt. | Annals of global health | 2020 | Yes |
| Chest physiotherapy in preterm infants with lung diseases. | Italian journal of pediatrics | 2010 | Yes |
| Substrate utilization and kinetics of surfactant metabolism in evolving bronchopulmonary dysplasia. | The Journal of pediatrics | 2005 | Yes |
| Randomised controlled trial of low dose fentanyl infusion in preterm infants with hyaline membrane disease. | Archives of disease in childhood. Fetal and neonatal edition | 1998 | Yes |
| Hyaline membrane disease in the newborn: diagnosis by ultrasound. | Pediatric radiology | 1990 | Yes |
Showing 5 of 22 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.