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Condition (MeSH)

Hypolipoproteinemias

ClinicalTrials.gov lists 91 trials for Hypolipoproteinemias or a narrower condition beneath it. IPCA Laboratories Ltd. has the most among industry and government lead sponsors, with 12.

MeSH D007009 Congenital / Hereditary / Neonatal C16 C18
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Phase 1 Phase 1 52 Phase 2 Phase 2 2 Phase 3 Phase 3 6 Phase 4 Phase 4 4 Not applicable Not applicable 15 Observational Observational 12 Phase 1 Phase 1 52 Phase 2 Phase 2 2 Phase 3 Phase 3 6 Phase 4 Phase 4 4 Not applicable Not applicable 15 Observational Observational 12

Trials per phase (log scale)

3 of the 91 trials are tagged with Hypolipoproteinemias itself; the rest are tagged with a narrower condition beneath it.

Get the Hypolipoproteinemias report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hypolipoproteinemias trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 15

1997: 1 trials (Observational 1) 1998: 1 trials (Phase 1 1) 1999: 3 trials (Phase 1 3) 2000: 1 trials (Observational 1) 2001: 2 trials (Phase 1 2) 2002: 4 trials (Phase 1 4) 2003: 1 trials (Phase 1 1) 2004: 2 trials (Phase 4 1, Phase 1 1) 2005: 3 trials (Phase 1 3) 2006: 5 trials (Not applicable 1, Phase 4 1, Phase 2 1, Phase 1 2) 2007: 2 trials (Phase 1 2) 2008: 1 trials (Phase 1 1) 2009: 1 trials (Not applicable 1) 2011: 9 trials (Phase 3 4, Phase 1 5) 2012: 15 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 1 12) 2013: 5 trials (Observational 1, Not applicable 1, Phase 2 1, Phase 1 2) 2014: 4 trials (Observational 1, Phase 1 3) 2015: 2 trials (Observational 1, Phase 3 1) 2016: 2 trials (Not applicable 2) 2017: 3 trials (Phase 1 3) 2018: 4 trials (Not applicable 3, Phase 3 1) 2019: 4 trials (Observational 2, Not applicable 1, Phase 4 1) 2022: 5 trials (Observational 2, Not applicable 1, Phase 1 2) 2023: 4 trials (Not applicable 2, Phase 1 2) 2024: 2 trials (Not applicable 2) 2025: 1 trials (Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 2
2025 1
2024 2
2023 4
2022 5
2019 4
2018 4
2017 3
2016 2
2015 2

No forecast is made for this condition: it averages 2.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hypolipoproteinemias trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 52
Phase 2 2
Phase 3 6
Phase 4 4
Not applicable 15
Observational 12

How many Hypolipoproteinemias trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 4
Active, not recruiting 1
Completed 77
Terminated 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hypolipoproteinemias trials? (9)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
IPCA Laboratories Ltd. 12
Par Pharmaceutical, Inc. 11
Dr. Reddy's Laboratories Limited 7
National Heart, Lung, and Blood Institute (NHLBI) 5
Pfizer 4

Which drugs are being tested for Hypolipoproteinemias? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
ROSUVASTATIN 2
Lisinopril 2

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
ER Niacin 2
PO Morphine 2
IM olanzapine 2
Ultracet 2
1% Metformin 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hypolipoproteinemias trials report? (8)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Liver-related death 24 1
Anaphylactic Reaction 1 1
Angina Unstable 1 1
Complication Associated with Device 1 1
Nasal septum disorder 1 1

Which publications cover Hypolipoproteinemias? (26)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Hypolipidemic and antioxidant activities of thymoquinone and limonene in atherogenic suspension fed rats. Food chemistry 2013 Yes
Molecular biology of PCSK9: its role in LDL metabolism. Trends in biochemical sciences 2007 Yes
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. The New England journal of medicine 2006 Yes
Clinical practice. Low HDL cholesterol levels. The New England journal of medicine 2005 Yes
Serum lipid levels in patients with dissociative disorder. The American journal of psychiatry 2004 Yes

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

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