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Condition (MeSH)

Erectile Dysfunction

ClinicalTrials.gov lists 666 trials for Erectile Dysfunction or a narrower condition beneath it. Bayer has the most among industry and government lead sponsors, with 51.

MeSH D007172 Urogenital Diseases C12 F03
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Phase 1 Phase 1 65 Phase 1/2 Phase 1/2 15 Phase 2 Phase 2 61 Phase 2/3 Phase 2/3 10 Phase 3 Phase 3 100 Phase 4 Phase 4 103 Not applicable Not applicable 197 Observational Observational 115 Phase 1 Phase 1 65 Phase 1/2 Phase 1/2 15 Phase 2 Phase 2 61 Phase 2/3 Phase 2/3 10 Phase 3 Phase 3 100 Phase 4 Phase 4 103 Not applicable Not applicable 197 Observational Observational 115

Trials per phase

666 of the 666 trials are tagged with Erectile Dysfunction itself; the rest are tagged with a narrower condition beneath it.

Get the Erectile Dysfunction report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Erectile Dysfunction trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 38

2000: 1 trials (Not applicable 1) 2001: 1 trials (Phase 2 1) 2002: 9 trials (Observational 1, Phase 4 2, Phase 3 5, Phase 2/3 1) 2003: 33 trials (Observational 1, Phase 4 14, Phase 3 17, Phase 2 1) 2004: 22 trials (Phase 4 13, Phase 3 7, Phase 2 1, Phase 1 1) 2005: 33 trials (Observational 7, Not applicable 2, Phase 4 15, Phase 3 4, Phase 2 5) 2006: 19 trials (Observational 2, Not applicable 3, Phase 4 5, Phase 3 4, Phase 2 3, Phase 1 2) 2007: 22 trials (Observational 8, Not applicable 3, Phase 4 4, Phase 3 2, Phase 2 1, Phase 1 4) 2008: 22 trials (Observational 3, Not applicable 2, Phase 4 4, Phase 3 5, Phase 2 2, Phase 1/2 1, Phase 1 5) 2009: 21 trials (Observational 2, Not applicable 1, Phase 4 7, Phase 3 8, Phase 2 3) 2010: 38 trials (Observational 6, Not applicable 4, Phase 4 3, Phase 3 9, Phase 2 4, Phase 1/2 1, Phase 1 11) 2011: 25 trials (Observational 5, Not applicable 3, Phase 4 2, Phase 3 9, Phase 2 3, Phase 1 3) 2012: 14 trials (Observational 3, Not applicable 3, Phase 4 6, Phase 3 2) 2013: 28 trials (Observational 8, Not applicable 9, Phase 4 3, Phase 3 3, Phase 2 1, Phase 1 4) 2014: 15 trials (Observational 3, Not applicable 6, Phase 4 3, Phase 3 1, Phase 1/2 1, Phase 1 1) 2015: 36 trials (Observational 7, Not applicable 11, Phase 2/3 1, Phase 2 8, Phase 1/2 2, Phase 1 7) 2016: 17 trials (Observational 3, Not applicable 6, Phase 4 3, Phase 3 2, Phase 2/3 1, Phase 2 1, Phase 1/2 1) 2017: 23 trials (Observational 8, Not applicable 7, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 1, Phase 1/2 2, Phase 1 2) 2018: 23 trials (Observational 3, Not applicable 14, Phase 4 1, Phase 3 1, Phase 2 2, Phase 1 2) 2019: 27 trials (Observational 5, Not applicable 14, Phase 4 2, Phase 3 1, Phase 2/3 1, Phase 2 1, Phase 1/2 2, Phase 1 1) 2020: 23 trials (Observational 4, Not applicable 9, Phase 3 1, Phase 2 6, Phase 1/2 1, Phase 1 2) 2021: 27 trials (Observational 4, Not applicable 13, Phase 4 1, Phase 3 5, Phase 2/3 1, Phase 2 1, Phase 1 2) 2022: 33 trials (Observational 5, Not applicable 12, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 3, Phase 1 10) 2023: 34 trials (Observational 2, Not applicable 22, Phase 4 2, Phase 3 3, Phase 2/3 1, Phase 2 1, Phase 1/2 2, Phase 1 1) 2024: 37 trials (Observational 6, Not applicable 21, Phase 4 1, Phase 3 4, Phase 2/3 1, Phase 2 3, Phase 1/2 1) 2025: 34 trials (Observational 8, Not applicable 13, Phase 4 4, Phase 3 3, Phase 2/3 1, Phase 1 5)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 44
2025 34
2024 37
2023 34
2022 33
2021 27
2020 23
2019 27
2018 23
2017 23

Forecast of the full-year count, planned starts included, not rows of this table: about 52 trials starting in 2026 and about 38 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 30 months from start to primary completion across 55 trials still running at the 2026-10-09 snapshot; registered median of 13 months across 340 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Erectile Dysfunction trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 65
Phase 1/2 15
Phase 2 61
Phase 2/3 10
Phase 3 100
Phase 4 103
Not applicable 197
Observational 115

How many Erectile Dysfunction trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 34
Recruiting 56
Enrolling by invitation 6
Active, not recruiting 16
Completed 378

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Erectile Dysfunction trials? (9)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Bayer 51
Eli Lilly and Company 28
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 27
VIVUS LLC 15
Vigonvita Life Sciences 10

Which drugs are being tested for Erectile Dysfunction? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
SILDENAFIL 67
AVANAFIL 16
Tamsulosin 6
Dapoxetine 5
DA-8159 4

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Tadalafil Pill 69
Vardenafil ODT (STAXYN, BAY38-9456) 53
[PRP] platelet rich plasma 12
Udenafil 8
SK3530 6

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Erectile Dysfunction trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Glucose, high (hyperglycemia) 32 1
Creatinine 16 1
ALT, SGPT 12 1
Device Infection 12 2
Hemoglobin 12 1

Which publications cover Erectile Dysfunction? (647)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages