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Condition (MeSH)

Genital Diseases, Male

ClinicalTrials.gov lists 9,189 trials for Genital Diseases, Male or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 220.

MeSH D005832 Urogenital Diseases C12
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Phase 1 Phase 1 1,007 Phase 1/2 Phase 1/2 449 Phase 2 Phase 2 1,764 Phase 2/3 Phase 2/3 113 Phase 3 Phase 3 797 Phase 4 Phase 4 393 Not applicable Not applicable 2,783 Observational Observational 1,853 Phase 1 Phase 1 1,007 Phase 1/2 Phase 1/2 449 Phase 2 Phase 2 1,764 Phase 2/3 Phase 2/3 113 Phase 3 Phase 3 797 Phase 4 Phase 4 393 Not applicable Not applicable 2,783 Observational Observational 1,853

Trials per phase (log scale)

2 more sections with rows

40 of the 9,189 trials are tagged with Genital Diseases, Male itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Genital Diseases, Male trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 15 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 543

1990: 5 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 1, Phase 1/2 1) 1991: 4 trials (Observational 1, Phase 2 1, Phase 1 2) 1992: 6 trials (Observational 1, Phase 3 3, Phase 2 2) 1993: 7 trials (Observational 5, Not applicable 1, Phase 2 1) 1994: 10 trials (Observational 1, Phase 3 5, Phase 1/2 3, Phase 1 1) 1995: 21 trials (Observational 3, Phase 3 10, Phase 2 3, Phase 1/2 1, Phase 1 4) 1996: 17 trials (Observational 3, Not applicable 1, Phase 3 6, Phase 2 6, Phase 1 1) 1997: 35 trials (Observational 1, Not applicable 7, Phase 3 6, Phase 2 11, Phase 1/2 2, Phase 1 8) 1998: 53 trials (Observational 5, Not applicable 2, Phase 4 3, Phase 3 11, Phase 2/3 1, Phase 2 18, Phase 1/2 3, Phase 1 10) 1999: 61 trials (Observational 4, Not applicable 3, Phase 3 18, Phase 2/3 1, Phase 2 18, Phase 1/2 5, Phase 1 12) 2000: 79 trials (Observational 9, Not applicable 4, Phase 3 12, Phase 2 33, Phase 1/2 6, Phase 1 15) 2001: 86 trials (Observational 6, Not applicable 6, Phase 4 1, Phase 3 14, Phase 2/3 2, Phase 2 38, Phase 1/2 6, Phase 1 13) 2002: 129 trials (Observational 20, Not applicable 13, Phase 4 8, Phase 3 19, Phase 2/3 4, Phase 2 47, Phase 1/2 8, Phase 1 10) 2003: 183 trials (Observational 19, Not applicable 19, Phase 4 30, Phase 3 44, Phase 2/3 1, Phase 2 49, Phase 1/2 8, Phase 1 13) 2004: 202 trials (Observational 31, Not applicable 20, Phase 4 24, Phase 3 31, Phase 2/3 3, Phase 2 63, Phase 1/2 12, Phase 1 18) 2005: 239 trials (Observational 38, Not applicable 39, Phase 4 24, Phase 3 34, Phase 2/3 3, Phase 2 62, Phase 1/2 15, Phase 1 24) 2006: 263 trials (Observational 34, Not applicable 43, Phase 4 21, Phase 3 33, Phase 2/3 8, Phase 2 71, Phase 1/2 20, Phase 1 33) 2007: 252 trials (Observational 40, Not applicable 40, Phase 4 13, Phase 3 30, Phase 2/3 2, Phase 2 82, Phase 1/2 7, Phase 1 38) 2008: 250 trials (Observational 43, Not applicable 44, Phase 4 13, Phase 3 27, Phase 2 73, Phase 1/2 14, Phase 1 36) 2009: 266 trials (Observational 44, Not applicable 54, Phase 4 15, Phase 3 45, Phase 2/3 4, Phase 2 60, Phase 1/2 14, Phase 1 30) 2010: 260 trials (Observational 59, Not applicable 45, Phase 4 10, Phase 3 33, Phase 2/3 3, Phase 2 53, Phase 1/2 17, Phase 1 40) 2011: 289 trials (Observational 54, Not applicable 67, Phase 4 17, Phase 3 35, Phase 2/3 4, Phase 2 63, Phase 1/2 10, Phase 1 39) 2012: 292 trials (Observational 50, Not applicable 85, Phase 4 22, Phase 3 23, Phase 2/3 5, Phase 2 65, Phase 1/2 13, Phase 1 29) 2013: 332 trials (Observational 71, Not applicable 98, Phase 4 14, Phase 3 23, Phase 2/3 4, Phase 2 73, Phase 1/2 15, Phase 1 34) 2014: 373 trials (Observational 78, Not applicable 123, Phase 4 18, Phase 3 27, Phase 2/3 3, Phase 2 69, Phase 1/2 12, Phase 1 43) 2015: 362 trials (Observational 89, Not applicable 114, Phase 4 13, Phase 3 20, Phase 2/3 2, Phase 2 58, Phase 1/2 16, Phase 1 50) 2016: 366 trials (Observational 78, Not applicable 121, Phase 4 15, Phase 3 24, Phase 2/3 8, Phase 2 62, Phase 1/2 15, Phase 1 43) 2017: 398 trials (Observational 92, Not applicable 153, Phase 4 12, Phase 3 14, Phase 2/3 3, Phase 2 72, Phase 1/2 15, Phase 1 37) 2018: 394 trials (Observational 68, Not applicable 170, Phase 4 7, Phase 3 16, Phase 2/3 7, Phase 2 77, Phase 1/2 19, Phase 1 30) 2019: 419 trials (Observational 100, Not applicable 143, Phase 4 14, Phase 3 24, Phase 2/3 7, Phase 2 67, Phase 1/2 20, Phase 1 44) 2020: 423 trials (Observational 111, Not applicable 141, Phase 4 5, Phase 3 35, Phase 2/3 7, Phase 2 57, Phase 1/2 19, Phase 1 48) 2021: 472 trials (Observational 107, Not applicable 178, Phase 4 13, Phase 3 31, Phase 2/3 7, Phase 2 69, Phase 1/2 19, Phase 1 48) 2022: 427 trials (Observational 104, Not applicable 192, Phase 4 6, Phase 3 20, Phase 2/3 2, Phase 2 47, Phase 1/2 16, Phase 1 40) 2023: 482 trials (Other 1, Observational 109, Not applicable 201, Phase 4 16, Phase 3 28, Phase 2/3 6, Phase 2 54, Phase 1/2 21, Phase 1 46) 2024: 543 trials (Observational 123, Not applicable 207, Phase 4 19, Phase 3 27, Phase 2/3 5, Phase 2 78, Phase 1/2 29, Phase 1 55) 2025: 517 trials (Observational 113, Not applicable 215, Phase 4 14, Phase 3 30, Phase 2/3 4, Phase 2 60, Phase 1/2 31, Phase 1 50)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 573
2025 517
2024 543
2023 482
2022 427
2021 472
2020 423
2019 419
2018 394
2017 398

Forecast of the full-year count, planned starts included, not rows of this table: about 700 trials starting in 2026 and about 570 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 1,044 trials still running at the 2026-10-09 snapshot; registered median of 30 months across 5,376 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Genital Diseases, Male trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1,007
Phase 1/2 449
Phase 2 1,764
Phase 2/3 113
Phase 3 797
Phase 4 393
Not applicable 2,783
Observational 1,853
Expanded access 29
Unknown 1

How many Genital Diseases, Male trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 401
Recruiting 1,282
Enrolling by invitation 62
Active, not recruiting 615
Available 6

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Genital Diseases, Male trials? (7)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 220
Bayer 101
AstraZeneca 70
GlaxoSmithKline 68
Eli Lilly and Company 60

Which drugs are being tested for Genital Diseases, Male? (7)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Prednisone 215
Abiraterone 212
Enzalutamide 193
Bicalutamide 112
Apalutamide 93

Interventions as named in the registry (8)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Docetetaxel 270
Lupron / Leuprolide acetate 121
Radiation Therapy 111
Tadalafil Pill 97
Goserelin Depot 95

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Genital Diseases, Male trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 1,487 208
Anaemia 1,151 156
Fatigue 950 171
Urinary tract infection 870 171
Dehydration 856 224

Which publications cover Genital Diseases, Male? (55)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (17)

MeSH descendants one level down with at least one trial, most trials first.

+7 more sub-conditions

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages