Condition (MeSH)
Varicocele
ClinicalTrials.gov lists 51 trials for Varicocele or a narrower condition beneath it. ArtVentive Medical Group, Inc. has the most among industry and government lead sponsors, with 1.
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Trials per phase (log scale)
51 of the 51 trials are tagged with Varicocele itself; the rest are tagged with a narrower condition beneath it.
When did Varicocele trials start? (19)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 2
- Phase 4
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 7 |
| 2025 | 4 |
| 2024 | 4 |
| 2023 | 1 |
| 2022 | 5 |
| 2021 | 1 |
| 2019 | 3 |
| 2018 | 1 |
| 2017 | 3 |
| 2016 | 5 |
Showing 10 of 19 earlier years.
No forecast is made for this condition: it averages 4.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Varicocele trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Phase 4 | 2 |
| Not applicable | 31 |
| Observational | 17 |
How many Varicocele trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 9 |
| Recruiting | 4 |
| Enrolling by invitation | 1 |
| Completed | 20 |
| Terminated | 2 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Varicocele trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| ArtVentive Medical Group, Inc. | 1 |
Which drugs are being tested for Varicocele? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Lidocaine 2 % | 1 |
Interventions as named in the registry (8)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| 0.5% Levobupivacaine | 1 |
| Spinal Anesthesia | 1 |
| Recombinant FSH | 1 |
| Live Attenuated Varicella Vaccine | 1 |
| Sclerotherapy | 1 |
Showing 5 of 8 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Varicocele trials report? (1)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Testicular Atrophy | 0 | 1 |
Which publications cover Varicocele? (78)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Does Sperm DNA Fragmentation Index Continuously Decrease Over Time After Varicocelectomy in Varicocele-Induced Infertility? A Systematic Review and Meta-Analysis. | American journal of men's health | 2024 | Yes |
| Pathophysiology and treatment options of varicocele: An overview. | Andrologia | 2021 | Yes |
| Semen Biochemical Components in Varicocele, Leukocytospermia, and Idiopathic Infertility. | Reproductive sciences (Thousand Oaks, Calif.) | 2021 | Yes |
| The effect of ejaculation time on varicose vein diameter and reflux level. | Andrologia | 2021 | Yes |
| The Negative Impact of Varicocele on Basic Semen Parameters, Sperm Nuclear DNA Dispersion and Oxidation-Reduction Potential in Semen. | International journal of environmental research and public health | 2021 | Yes |
Showing 5 of 78 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.