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Condition (MeSH)

Insulinoma

ClinicalTrials.gov lists 62 trials for Insulinoma or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 8.

MeSH D007340 Neoplasms Neoplasm C04 C06 C19
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Phase 1 Phase 1 15 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 22 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Not applicable Not applicable 8 Observational Observational 9 Expanded access Expanded access 3 Phase 1 Phase 1 15 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 22 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Not applicable Not applicable 8 Observational Observational 9 Expanded access Expanded access 3

Trials per phase (log scale)

62 of the 62 trials are tagged with Insulinoma itself; the rest are tagged with a narrower condition beneath it.

Get the Insulinoma report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Insulinoma trials start? (28)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Not applicable
  • Observational

Top of scale: 5

1991: 1 trials (Observational 1) 1996: 1 trials (Phase 1 1) 1998: 1 trials (Phase 1 1) 1999: 1 trials (Phase 1 1) 2000: 3 trials (Not applicable 1, Phase 1 2) 2001: 2 trials (Phase 2 2) 2002: 1 trials (Phase 1 1) 2003: 2 trials (Phase 2 2) 2004: 4 trials (Phase 2 3, Phase 1 1) 2005: 3 trials (Phase 2/3 1, Phase 2 2) 2006: 2 trials (Observational 1, Phase 3 1) 2007: 3 trials (Observational 1, Phase 3 1, Phase 2 1) 2008: 1 trials (Phase 2 1) 2009: 1 trials (Not applicable 1) 2010: 3 trials (Observational 1, Phase 2 1, Phase 1 1) 2012: 1 trials (Phase 2 1) 2013: 2 trials (Phase 2 1, Phase 1 1) 2014: 5 trials (Not applicable 1, Phase 2 3, Phase 1 1) 2015: 1 trials (Phase 1/2 1) 2016: 1 trials (Phase 2 1) 2017: 2 trials (Phase 2 1, Phase 1 1) 2018: 2 trials (Observational 1, Phase 1 1) 2019: 4 trials (Observational 1, Not applicable 2, Phase 1 1) 2020: 2 trials (Phase 2 1, Phase 1 1) 2021: 1 trials (Phase 1 1) 2023: 4 trials (Observational 1, Not applicable 2, Phase 2 1) 2025: 3 trials (Observational 2, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 3
2023 4
2021 1
2020 2
2019 4
2018 2
2017 2
2016 1
2015 1

No forecast is made for this condition: it averages 1.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Insulinoma trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 15
Phase 1/2 1
Phase 2 22
Phase 2/3 1
Phase 3 3
Not applicable 8
Observational 9
Expanded access 3

How many Insulinoma trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 8
Active, not recruiting 2
Available 2
Completed 27
Terminated 9

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Insulinoma trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 8
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 3
ECOG-ACRIN Cancer Research Group 2
Eastern Cooperative Oncology Group 2

Which drugs are being tested for Insulinoma? (6)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
"Capecitabine" 4
EVEROLIMUS 4
Calcium Leucovorin 3
OXALIPLATIN 2
18F-DOPA 2

Interventions as named in the registry (9)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
LAR Octreotide 4
SOC: Temozolomide 3
Fluorouracile 2
Bortezomib SC 2
Bevacizumab 1 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Insulinoma trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Abdominal pain 29 5
Fatigue 29 4
Nausea 25 5
Vomiting 20 5
Diarrhea 17 5

Which publications cover Insulinoma? (31)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Prevalence (8)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Insulinoma Annual incidence 1-9 / 1 000 000 Ireland Not stated Exact
Insulinoma Point prevalence Unknown Europe Not stated Exact
Insulinoma Point prevalence Unknown Europe Not stated Exact
Insulinoma Annual incidence 1-9 / 1 000 000 Ireland Not stated Exact
Insulinoma Point prevalence 1-9 / 1 000 000 Japan Not stated Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Insulinoma 97279 Exact Orphadata Science knowledge files, Product 1
Insulinoma 97279 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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