Condition (MeSH)
Klippel-Feil Syndrome
ClinicalTrials.gov lists 27 trials for Klippel-Feil Syndrome or a narrower condition beneath it. Providence Medical Technology, Inc. has the most among industry and government lead sponsors, with 2.
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Trials per phase
27 of the 27 trials are tagged with Klippel-Feil Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Klippel-Feil Syndrome trials start? (13)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 4
- Not applicable
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 1 |
| 2023 | 4 |
| 2022 | 4 |
| 2021 | 2 |
| 2020 | 3 |
| 2019 | 3 |
| 2018 | 2 |
| 2017 | 1 |
| 2015 | 2 |
Showing 10 of 13 earlier years.
No forecast is made for this condition: it averages 2.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 33 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 24 months across 12 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Klippel-Feil Syndrome trials in? (3)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 4 | 4 |
| Not applicable | 13 |
| Observational | 10 |
How many Klippel-Feil Syndrome trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 6 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 3 |
| Completed | 8 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Klippel-Feil Syndrome trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Providence Medical Technology, Inc. | 2 |
| Aesculap AG | 1 |
| Biobank | 1 |
| LifeNet Health | 1 |
| MT Ortho s.r.l. | 1 |
Which drugs are being tested for Klippel-Feil Syndrome? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| PMI-150 (intranasal ketamine) | 2 |
Interventions as named in the registry (5)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Trigger point injection with bupivacaine | 1 |
| Bupivacaine Hcl 0.25% Inj | 1 |
| Opioids | 1 |
| Observational Study | 1 |
| Lidocaine skin wheal | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Klippel-Feil Syndrome? (7)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Airway management in newborn with Klippel-Feil syndrome. | Brazilian journal of anesthesiology (Elsevier) | 2016 | Yes |
| The success of direct laryngoscopy in children with Klippel-Feil Syndrome. | Minerva anestesiologica | 2015 | Yes |
| Repeated anesthetic management for a patient with Klippel-Feil syndrome. | Anesthesia progress | 2014 | Yes |
| Crisis resource management of the airway in a patient with Klippel-Feil syndrome, congenital deafness, and aortic dissection. | Anesthesia and analgesia | 2009 | Yes |
| Congenital cervical spine fusion and airway management: a case series of Klippel-Feil syndrome. | Journal of clinical anesthesia | 2008 | Yes |
Showing 5 of 7 publications.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Isolated Klippel-Feil syndrome | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Exact |
| Isolated Klippel-Feil syndrome | Prevalence at birth | 1-9 / 1 000 000 | Europe | Not stated | Unspecified |
| Isolated Klippel-Feil syndrome | Prevalence at birth | 1-9 / 1 000 000 | Europe | Not stated | Exact |
| Isolated Klippel-Feil syndrome | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Unspecified |
| Isolated Klippel-Feil syndrome | Point prevalence | 1-9 / 100 000 | Europe | Not stated | Exact |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Isolated Klippel-Feil syndrome | 2345 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Isolated Klippel-Feil syndrome | 2345 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.