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Condition (MeSH)

Leukemia

ClinicalTrials.gov lists 8,760 trials for Leukemia or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 428.

MeSH D007938 Neoplasms Neoplasm C04 C15
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Phase 1 Phase 1 2,119 Phase 1/2 Phase 1/2 1,026 Phase 2 Phase 2 2,486 Phase 2/3 Phase 2/3 131 Phase 3 Phase 3 667 Phase 4 Phase 4 173 Not applicable Not applicable 802 Observational Observational 1,305 Phase 1 Phase 1 2,119 Phase 1/2 Phase 1/2 1,026 Phase 2 Phase 2 2,486 Phase 2/3 Phase 2/3 131 Phase 3 Phase 3 667 Phase 4 Phase 4 173 Not applicable Not applicable 802 Observational Observational 1,305

Trials per phase

2 more sections with rows

2,378 of the 8,760 trials are tagged with Leukemia itself; the rest are tagged with a narrower condition beneath it.

Get the Leukemia report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Leukemia trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 24 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access, Unknown)

Top of scale: 417

1990: 7 trials (Not applicable 1, Phase 2/3 1, Phase 2 4, Phase 1 1) 1991: 5 trials (Observational 1, Phase 2 3, Phase 1 1) 1992: 10 trials (Observational 2, Not applicable 1, Phase 3 1, Phase 2 4, Phase 1/2 1, Phase 1 1) 1993: 22 trials (Observational 2, Not applicable 2, Phase 4 1, Phase 3 7, Phase 2 8, Phase 1 2) 1994: 20 trials (Observational 2, Phase 3 3, Phase 2 12, Phase 1 3) 1995: 36 trials (Observational 3, Not applicable 1, Phase 4 1, Phase 3 9, Phase 2/3 1, Phase 2 10, Phase 1/2 6, Phase 1 5) 1996: 55 trials (Observational 5, Not applicable 2, Phase 4 2, Phase 3 13, Phase 2 19, Phase 1/2 3, Phase 1 11) 1997: 57 trials (Observational 2, Not applicable 3, Phase 4 1, Phase 3 11, Phase 2/3 1, Phase 2 22, Phase 1/2 4, Phase 1 13) 1998: 110 trials (Observational 8, Not applicable 2, Phase 4 3, Phase 3 17, Phase 2/3 2, Phase 2 46, Phase 1/2 7, Phase 1 25) 1999: 138 trials (Observational 6, Not applicable 7, Phase 4 2, Phase 3 19, Phase 2/3 2, Phase 2 49, Phase 1/2 13, Phase 1 40) 2000: 155 trials (Observational 9, Not applicable 10, Phase 4 5, Phase 3 24, Phase 2/3 2, Phase 2 66, Phase 1/2 13, Phase 1 26) 2001: 137 trials (Observational 11, Not applicable 14, Phase 4 1, Phase 3 10, Phase 2/3 3, Phase 2 58, Phase 1/2 17, Phase 1 23) 2002: 156 trials (Observational 10, Not applicable 7, Phase 4 2, Phase 3 22, Phase 2/3 1, Phase 2 63, Phase 1/2 17, Phase 1 34) 2003: 162 trials (Observational 14, Not applicable 14, Phase 4 11, Phase 3 18, Phase 2/3 1, Phase 2 61, Phase 1/2 17, Phase 1 26) 2004: 222 trials (Observational 16, Not applicable 12, Phase 4 4, Phase 3 23, Phase 2/3 7, Phase 2 90, Phase 1/2 21, Phase 1 49) 2005: 245 trials (Observational 20, Not applicable 10, Phase 4 9, Phase 3 20, Phase 2/3 1, Phase 2 94, Phase 1/2 35, Phase 1 56) 2006: 247 trials (Other 2, Observational 20, Not applicable 16, Phase 4 3, Phase 3 15, Phase 2/3 6, Phase 2 97, Phase 1/2 31, Phase 1 57) 2007: 277 trials (Other 1, Observational 24, Not applicable 20, Phase 4 6, Phase 3 29, Phase 2/3 1, Phase 2 93, Phase 1/2 33, Phase 1 70) 2008: 283 trials (Other 1, Observational 37, Not applicable 22, Phase 4 4, Phase 3 24, Phase 2/3 5, Phase 2 100, Phase 1/2 31, Phase 1 59) 2009: 295 trials (Other 1, Observational 45, Not applicable 16, Phase 4 7, Phase 3 29, Phase 2/3 5, Phase 2 91, Phase 1/2 31, Phase 1 70) 2010: 331 trials (Other 1, Observational 66, Not applicable 17, Phase 4 14, Phase 3 19, Phase 2/3 2, Phase 2 100, Phase 1/2 32, Phase 1 80) 2011: 292 trials (Observational 50, Not applicable 12, Phase 4 5, Phase 3 18, Phase 2/3 2, Phase 2 104, Phase 1/2 34, Phase 1 67) 2012: 289 trials (Observational 43, Not applicable 13, Phase 4 3, Phase 3 28, Phase 2/3 1, Phase 2 94, Phase 1/2 35, Phase 1 72) 2013: 287 trials (Observational 43, Not applicable 16, Phase 4 13, Phase 3 20, Phase 2/3 5, Phase 2 92, Phase 1/2 38, Phase 1 60) 2014: 283 trials (Observational 43, Not applicable 21, Phase 4 4, Phase 3 29, Phase 2/3 3, Phase 2 61, Phase 1/2 39, Phase 1 83) 2015: 307 trials (Observational 31, Not applicable 33, Phase 4 7, Phase 3 18, Phase 2/3 6, Phase 2 89, Phase 1/2 45, Phase 1 78) 2016: 345 trials (Observational 49, Not applicable 19, Phase 4 9, Phase 3 22, Phase 2/3 9, Phase 2 81, Phase 1/2 58, Phase 1 98) 2017: 344 trials (Observational 62, Not applicable 30, Phase 4 5, Phase 3 22, Phase 2/3 3, Phase 2 83, Phase 1/2 55, Phase 1 84) 2018: 350 trials (Observational 65, Not applicable 27, Phase 4 3, Phase 3 20, Phase 2/3 11, Phase 2 83, Phase 1/2 42, Phase 1 99) 2019: 377 trials (Observational 54, Not applicable 45, Phase 4 8, Phase 3 29, Phase 2/3 6, Phase 2 87, Phase 1/2 46, Phase 1 102) 2020: 397 trials (Observational 93, Not applicable 37, Phase 4 1, Phase 3 16, Phase 2/3 4, Phase 2 81, Phase 1/2 49, Phase 1 116) 2021: 417 trials (Observational 79, Not applicable 57, Phase 4 9, Phase 3 25, Phase 2/3 5, Phase 2 82, Phase 1/2 53, Phase 1 107) 2022: 414 trials (Observational 90, Not applicable 60, Phase 4 7, Phase 3 21, Phase 2/3 4, Phase 2 68, Phase 1/2 51, Phase 1 113) 2023: 388 trials (Observational 93, Not applicable 64, Phase 4 5, Phase 3 20, Phase 2/3 3, Phase 2 67, Phase 1/2 42, Phase 1 94) 2024: 417 trials (Observational 77, Not applicable 59, Phase 4 8, Phase 3 16, Phase 2/3 3, Phase 2 104, Phase 1/2 45, Phase 1 105) 2025: 394 trials (Observational 61, Not applicable 64, Phase 4 6, Phase 3 19, Phase 2/3 13, Phase 2 94, Phase 1/2 41, Phase 1 96)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 379
2025 394
2024 417
2023 388
2022 414
2021 417
2020 397
2019 377
2018 350
2017 344

Forecast of the full-year count, planned starts included, not rows of this table: about 410 trials starting in 2026 and about 410 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 1,031 trials still running at the 2026-10-09 snapshot; registered median of 41 months across 5,356 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Leukemia trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 2,119
Phase 1/2 1,026
Phase 2 2,486
Phase 2/3 131
Phase 3 667
Phase 4 173
Not applicable 802
Observational 1,305
Expanded access 49
Unknown 2

How many Leukemia trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 299
Recruiting 1,214
Enrolling by invitation 42
Active, not recruiting 553
Available 12

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Leukemia trials? (5)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 428
Novartis Pharmaceuticals 163
Children's Oncology Group 155
AbbVie 75
Bristol-Myers Squibb 64

Which drugs are being tested for Leukemia? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Cytoxan 774
RITUXIMAB 376
Busulfan 251

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Cytarabine IT 753
SQ Fludarabine 668
Venetoclax 600 447
Azacitidine MTD 376
HD- Methotrexate (MTX) 361

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Leukemia trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Febrile neutropenia 9,099 633
Pneumonia 5,915 529
Neutrophil count decreased 4,350 207
Platelet count decreased 3,952 239
Sepsis 3,928 677

Which publications cover Leukemia? (797)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (7)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages