Condition (MeSH)
Macroglossia
ClinicalTrials.gov lists 6 trials for Macroglossia or a narrower condition beneath it. CENTOGENE GmbH Rostock has the most among industry and government lead sponsors, with 2.
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Trials per phase
6 of the 6 trials are tagged with Macroglossia itself; the rest are tagged with a narrower condition beneath it.
When did Macroglossia trials start? (3)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2023 | 1 |
| 2019 | 1 |
| 2018 | 4 |
No forecast is made for this condition: it averages 0.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 6 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Macroglossia trials in? (2)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Observational | 5 |
How many Macroglossia trials are recruiting? (2)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Completed | 4 |
| Withdrawn | 2 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Macroglossia trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| CENTOGENE GmbH Rostock | 2 |
| SWOG Cancer Research Network | 1 |
Which serious adverse events do Macroglossia trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Hypokalemia | 3 | 1 |
| Lung infection | 3 | 1 |
| Abdominal pain | 2 | 1 |
| Dyspnea | 2 | 1 |
| Fever | 2 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Macroglossia? (4)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Efficacy of sirolimus in the treatment of microcystic lymphatic malformation of the tongue. | Journal of the European Academy of Dermatology and Venereology : JEADV | 2019 | Yes |
| Overview of macroglossia and its treatment. | Current opinion in otolaryngology & head and neck surgery | 2009 | Yes |
| Drooling, chewing and swallowing dysfunctions in children with cerebral palsy: treatment according to Castillo-Morales. | ASDC journal of dentistry for children | 1990 | Yes |
| The clinical features of immunoglobulin light-chain (AL) amyloidosis with heart involvement. | QJM : monthly journal of the Association of Physicians | 1998 | No |
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Macroglossia | 156207 | Exact | Orphadata Science knowledge files, Product 1 |
| Macroglossia | 156207 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.