Condition (MeSH)
Tongue Diseases
ClinicalTrials.gov lists 156 trials for Tongue Diseases or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 20.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
2 of the 156 trials are tagged with Tongue Diseases itself; the rest are tagged with a narrower condition beneath it.
When did Tongue Diseases trials start? (28)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 14
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 7 |
| 2024 | 2 |
| 2023 | 4 |
| 2022 | 1 |
| 2021 | 5 |
| 2020 | 5 |
| 2019 | 5 |
| 2018 | 14 |
| 2017 | 6 |
Showing 10 of 28 earlier years.
No forecast is made for this condition: it averages 3.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 38 months across 111 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Tongue Diseases trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 18 |
| Phase 1/2 | 13 |
| Phase 2 | 35 |
| Phase 2/3 | 1 |
| Phase 3 | 10 |
| Phase 4 | 5 |
| Not applicable | 37 |
| Observational | 37 |
How many Tongue Diseases trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 13 |
| Active, not recruiting | 5 |
| Completed | 92 |
| Suspended | 1 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Tongue Diseases trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Cancer Institute (NCI) | 20 |
| Alpha Tau Medical LTD. | 5 |
| Radiation Therapy Oncology Group | 3 |
| CENTOGENE GmbH Rostock | 2 |
| European Organisation for Research and Treatment of Cancer - EORTC | 2 |
Which drugs are being tested for Tongue Diseases? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| CETUXIMAB | 16 |
| EVEROLIMUS | 4 |
| Sorafenib | 3 |
| (nab)-paclitaxel | 3 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Cisplatin 1 | 16 |
| Docetetaxel | 7 |
| Radiation Therapy | 6 |
| Doxycline | 6 |
| or carboplatin | 4 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Tongue Diseases trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Neutrophil count decreased | 137 | 3 |
| Mucositis oral | 103 | 4 |
| White blood cell decreased | 92 | 4 |
| Dehydration | 86 | 11 |
| Fatigue | 80 | 7 |
Showing 5 of 10 adverse events.
Which publications cover Tongue Diseases? (42)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Application value of indocyanine green lymphography in the management of stage I/IIA microcystic lymphatic malformation of the tongue. | Head & face medicine | 2025 | Yes |
| Can Tonsillar Retractor-Induced Tongue Edema Be a New Complication in Pediatric Patients Undergoing Tonsillectomy Detected by Ultrasonography? A Prospective, Case-Controlled, Observational Study. | Ear, nose, & throat journal | 2022 | Yes |
| Rehabilitation Protocol for Unilateral Laryngeal and Lingual Paralysis (Tapia Syndrome): Comment About "A Challenging Case of Tapia Syndrome After Total Thyroidectomy" By Ildem Deveci, Mehmet Surmeli, and Reyhan Surmeli. | Ear, nose, & throat journal | 2021 | Yes |
| Use of an improvised clamp to manage bleeding tongue injuries. | The American journal of emergency medicine | 2021 | Yes |
| The tongue features associated with chronic kidney disease. | Medicine | 2021 | Yes |
Showing 5 of 42 publications.
Sub-conditions in MeSH (6)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.