Condition (MeSH)
Otitis Externa
ClinicalTrials.gov lists 12 trials for Otitis Externa or a narrower condition beneath it. Otic Pharma has the most among industry and government lead sponsors, with 3.
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Trials per phase
12 of the 12 trials are tagged with Otitis Externa itself; the rest are tagged with a narrower condition beneath it.
When did Otitis Externa trials start? (10)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Phase 2
- Phase 3
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2022 | 1 |
| 2016 | 1 |
| 2015 | 2 |
| 2013 | 1 |
| 2012 | 1 |
| 2011 | 1 |
| 2010 | 1 |
| 2009 | 1 |
| 2008 | 2 |
No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 12 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Otitis Externa trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 1 |
| Phase 2 | 4 |
| Phase 3 | 4 |
| Not applicable | 2 |
| Observational | 1 |
How many Otitis Externa trials are recruiting? (3)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 1 |
| Completed | 8 |
| Terminated | 3 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Otitis Externa trials? (7)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Otic Pharma | 3 |
| Otonomy, Inc. | 2 |
| Alcon Research | 1 |
| Bitop AG | 1 |
| Circius Pharma AB | 1 |
Showing 5 of 7 sponsors.
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| 0.3% Ciprofloxacin Ear Drops | 2 |
| Dexamethasone phosphate otic solution | 1 |
| Diclofenac 3% | 1 |
| dexotc | 1 |
| CIPRODEX® (ciprofloxacin 0.3%/dexamethasone 0.1%) | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Otitis Externa? (11)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Head-to-Head Comparison Between <sup>18</sup>F-FDG PET and Leukocyte Scintigraphy to Monitor Treatment Responses in Necrotizing Otitis Externa. | Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale | 2024 | Yes |
| Efficacy and Safety of Ciprofloxacin Plus Fluocinolone Acetonide Among Patients With Acute Otitis Externa: A Randomized Clinical Trial. | JAMA network open | 2022 | Yes |
| Oxythiamine improves antifungal activity of ketoconazole evaluated in canine Malassezia pachydermatis strains. | Veterinary dermatology | 2018 | Yes |
| Ciprofloxacin 0.3%/dexamethasone 0.1% sterile otic suspension for the topical treatment of ear infections: a review of the literature. | The Pediatric infectious disease journal | 2009 | Yes |
| Otomycosis: clinical features and treatment implications. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | 2006 | Yes |
Showing 5 of 11 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.