Condition (MeSH)
Pemphigus
ClinicalTrials.gov lists 73 trials for Pemphigus or a narrower condition beneath it.
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Trials per phase
1 more section with rows
73 of the 73 trials are tagged with Pemphigus itself; the rest are tagged with a narrower condition beneath it.
When did Pemphigus trials start? (25)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 6 |
| 2024 | 6 |
| 2023 | 2 |
| 2022 | 5 |
| 2021 | 7 |
| 2020 | 5 |
| 2019 | 5 |
| 2018 | 1 |
| 2017 | 5 |
Showing 10 of 25 earlier years.
No forecast is made for this condition: it averages 4.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 32 months across 35 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Pemphigus trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 6 |
| Phase 1/2 | 3 |
| Phase 2 | 17 |
| Phase 2/3 | 3 |
| Phase 3 | 11 |
| Phase 4 | 3 |
| Not applicable | 8 |
| Observational | 21 |
| Expanded access | 1 |
How many Pemphigus trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 6 |
| Recruiting | 7 |
| Active, not recruiting | 3 |
| Available | 1 |
| Completed | 27 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Pemphigus trials? (8)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | 3 |
| argenx | 3 |
| Hoffmann-La Roche | 2 |
| Novartis Pharmaceuticals | 2 |
| Principia Biopharma, a Sanofi Company | 2 |
Showing 5 of 8 sponsors.
Which drugs are being tested for Pemphigus? (5)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| RITUXIMAB | 9 |
| Cytoxan | 3 |
| Prednisone | 3 |
| CM313 | 2 |
| Rilzabrutinib | 2 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Ofatumumab 300 | 3 |
| Glucocorticoids | 2 |
| Efgartigimod PH20 (ARGX-113) SC | 2 |
| CABA-201 | 1 |
| Prednisone/ prednisolone | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Pemphigus trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Covid-19 | 8 | 1 |
| COVID-19 | 7 | 3 |
| PEMPHIGUS | 6 | 2 |
| Pemphigus | 6 | 5 |
| Covid-19 Pneumonia | 4 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Pemphigus? (134)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| The emerging role of T cells in pemphigus vulgaris: a systematic review. | Clinical and experimental medicine | 2023 | Yes |
| Immune cells in pemphigus vulgaris and bullous Pemphigoid: From pathogenic roles to targeting therapies. | International immunopharmacology | 2023 | Yes |
| Microenvironmental network of clonal CXCL13+CD4+ T cells and Tregs in pemphigus chronic blisters. | The Journal of clinical investigation | 2023 | Yes |
| Utility of oral mucosa as a substrate for the serodiagnosis of pemphigus: A descriptive analysis. | Indian journal of dermatology, venereology and leprology | 2022 | Yes |
| Serum and tissue levels of coenzyme Q10 in pemphigus vulgaris. | Journal of cosmetic dermatology | 2022 | Yes |
Showing 5 of 134 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.