Condition (MeSH)
Peutz-Jeghers Syndrome
ClinicalTrials.gov lists 21 trials for Peutz-Jeghers Syndrome or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
21 of the 21 trials are tagged with Peutz-Jeghers Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Peutz-Jeghers Syndrome trials start? (15)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2023 | 2 |
| 2022 | 2 |
| 2019 | 1 |
| 2018 | 2 |
| 2017 | 1 |
| 2015 | 1 |
| 2014 | 2 |
| 2013 | 1 |
| 2012 | 1 |
Showing 10 of 15 earlier years.
No forecast is made for this condition: it averages 1.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Peutz-Jeghers Syndrome trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 1 |
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 2 |
| Not applicable | 4 |
| Observational | 11 |
How many Peutz-Jeghers Syndrome trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 5 |
| Active, not recruiting | 1 |
| Completed | 7 |
| Terminated | 2 |
| Withdrawn | 2 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Peutz-Jeghers Syndrome trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1 |
| National Cancer Institute (NCI) | 1 |
Which drugs are being tested for Peutz-Jeghers Syndrome? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| EVEROLIMUS | 2 |
| Synthetic Human Secretin | 1 |
| Sirolimus | 1 |
Interventions as named in the registry (6)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| data collection | 1 |
| Secretin | 1 |
| oCRH | 1 |
| Secretin (human synthetic) - ChiRhoClin | 1 |
| MRI | 1 |
Showing 5 of 6 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Peutz-Jeghers Syndrome? (24)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| The role of double-balloon enteroscopy in reducing the maximum size of polyps in patients with Peutz-Jeghers syndrome: 12-year experience. | Journal of digestive diseases | 2019 | Yes |
| Chemoprevention in Patients with Peutz-Jeghers Syndrome: Lessons Learned. | The oncologist | 2018 | Yes |
| Cancer risk in patients with Peutz-Jeghers syndrome: A retrospective cohort study of 336 cases. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine | 2017 | Yes |
| Guideline for wireless capsule endoscopy in children and adolescents: A consensus document by the SEGHNP (Spanish Society for Pediatric Gastroenterology, Hepatology, and Nutrition) and the SEPD (Spanish Society for Digestive Diseases). | Revista espanola de enfermedades digestivas | 2015 | Yes |
| ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. | The American journal of gastroenterology | 2015 | Yes |
Showing 5 of 24 publications.
Prevalence (9)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Peutz-Jeghers syndrome | Prevalence at birth | 1-9 / 100 000 | Worldwide | Not stated | Exact |
| Peutz-Jeghers syndrome | Prevalence at birth | 1-9 / 1 000 000 | Uruguay | Not stated | Exact |
| Peutz-Jeghers syndrome | Prevalence at birth | 1-9 / 100 000 | Worldwide | Not stated | Exact |
| Peutz-Jeghers syndrome | Prevalence at birth | 1-9 / 100 000 | Worldwide | Not stated | Unspecified |
| Peutz-Jeghers syndrome | Point prevalence | 1-9 / 1 000 000 | Europe | Not stated | Unspecified |
Showing 5 of 9 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Peutz-Jeghers syndrome | 2869 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Peutz-Jeghers syndrome | 2869 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.