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Condition (MeSH)

Prognathism

ClinicalTrials.gov lists 10 trials for Prognathism or a narrower condition beneath it. National Institute of Dental and Craniofacial Research (NIDCR) has the most among industry and government lead sponsors, with 1.

MeSH D011378 Musculoskeletal Diseases C05 C07 C16
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Phase 1/2 Phase 1/2 1 Phase 2/3 Phase 2/3 1 Not applicable Not applicable 3 Observational Observational 5 Phase 1/2 Phase 1/2 1 Phase 2/3 Phase 2/3 1 Not applicable Not applicable 3 Observational Observational 5

Trials per phase

10 of the 10 trials are tagged with Prognathism itself; the rest are tagged with a narrower condition beneath it.

Get the Prognathism report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Prognathism trials start? (9)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1/2
  • Phase 2/3
  • Not applicable
  • Observational

Top of scale: 2

2013: 1 trials (Not applicable 1) 2014: 1 trials (Observational 1) 2016: 1 trials (Observational 1) 2017: 1 trials (Not applicable 1) 2020: 1 trials (Observational 1) 2021: 1 trials (Not applicable 1) 2022: 1 trials (Phase 2/3 1) 2024: 1 trials (Phase 1/2 1) 2025: 2 trials (Observational 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 2
2024 1
2022 1
2021 1
2020 1
2017 1
2016 1
2014 1
2013 1

No forecast is made for this condition: it averages 1.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Prognathism trials in? (4)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1/2 1
Phase 2/3 1
Not applicable 3
Observational 5

How many Prognathism trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 2
Enrolling by invitation 1
Completed 2
Unknown status 4

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Prognathism trials? (1)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute of Dental and Craniofacial Research (NIDCR) 1

Which drugs are being tested for Prognathism? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Hydroxocobalamin 1

Interventions as named in the registry (4)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Questionnaire and Physical Exam 1
Melatonin PR 1
10% Iron Isomaltoside 1000 1
Centrum 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Prognathism? (36)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Short-term soft- and hard-tissue changes following Class III treatment using a removable mandibular retractor: a randomized controlled trial. Orthodontics & craniofacial research 2013 Yes
Treatment outcome analysis of speedy surgical orthodontics for adults with maxillary protrusion. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2011 Yes
Miniscrew-assisted nonsurgical palatal expansion before orthognathic surgery for a patient with severe mandibular prognathism. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2010 Yes
Relationship between inferior alveolar nerve canal position at mandibular second molar in patients with prognathism and possible occurrence of neurosensory disturbance after sagittal split ramus osteotomy. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2010 Yes
A Surgery-first approach in surgical-orthodontic treatment of mandibular prognathism--a case report. Chang Gung medical journal 2010 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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