Condition (MeSH)
Thyroid Nodule
ClinicalTrials.gov lists 183 trials for Thyroid Nodule or a narrower condition beneath it. Umraniye Education and Research Hospital has the most among industry and government lead sponsors, with 3.
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Trials per phase (log scale)
183 of the 183 trials are tagged with Thyroid Nodule itself; the rest are tagged with a narrower condition beneath it.
When did Thyroid Nodule trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
- Expanded access
Top of scale: 17
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 9 |
| 2025 | 14 |
| 2024 | 16 |
| 2023 | 12 |
| 2022 | 16 |
| 2021 | 12 |
| 2020 | 17 |
| 2019 | 9 |
| 2018 | 6 |
| 2017 | 16 |
Showing 10 of 24 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 10 trials starting in 2026 and about 13 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 19 trials still running at the 2026-10-09 snapshot; registered median of 22 months across 84 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Thyroid Nodule trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 2/3 | 1 |
| Phase 3 | 2 |
| Phase 4 | 7 |
| Not applicable | 90 |
| Observational | 78 |
| Expanded access | 1 |
How many Thyroid Nodule trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 8 |
| Recruiting | 36 |
| Enrolling by invitation | 3 |
| Active, not recruiting | 2 |
| Available | 1 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Thyroid Nodule trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Umraniye Education and Research Hospital | 3 |
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Contrast Enhanced Ultrasound (CEUS) | 2 |
| Active Surveillance (study visit Day 1, Day 2 and Day 7) | 2 |
| 1% Metformin | 2 |
| Amoxicillin and clavulanate | 2 |
| 98% dehydrated alcohol | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Thyroid Nodule? (278)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Improvement in thyroid-specific quality of life following radiofrequency ablation of benign thyroid nodules: A USA study. | Surgery | 2025 | Yes |
| High Water Iodine Concentrations Are Associated With the Prevalence of Subclinical Hypothyroidism, Thyroid Nodules, and Goiter Among Pregnant Women in Shandong, China. | The Journal of nutrition | 2025 | Yes |
| Deep learning model for malignancy prediction of TI-RADS 4 thyroid nodules with high-risk characteristics using multimodal ultrasound: A multicentre study. | Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society | 2025 | Yes |
| Multi-modal convolutional neural network-based thyroid cytology classification and diagnosis. | Human pathology | 2025 | Yes |
| Thyroid ultrasound and its ancillary techniques. | Reviews in endocrine & metabolic disorders | 2024 | Yes |
Showing 5 of 278 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.