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Condition (MeSH)

Neoplasms by Site

ClinicalTrials.gov lists 72,505 trials for Neoplasms by Site or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 2,029.

MeSH D009371 Neoplasms Neoplasm C04
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Phase 1 Phase 1 8,455 Phase 1/2 Phase 1/2 4,529 Phase 2 Phase 2 18,513 Phase 2/3 Phase 2/3 856 Phase 3 Phase 3 5,992 Phase 4 Phase 4 1,302 Not applicable Not applicable 16,636 Observational Observational 16,030 Phase 1 Phase 1 8,455 Phase 1/2 Phase 1/2 4,529 Phase 2 Phase 2 18,513 Phase 2/3 Phase 2/3 856 Phase 3 Phase 3 5,992 Phase 4 Phase 4 1,302 Not applicable Not applicable 16,636 Observational Observational 16,030

Trials per phase (log scale)

2 more sections with rows

207 of the 72,505 trials are tagged with Neoplasms by Site itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Neoplasms by Site trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 155 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access, Unknown)

Top of scale: 4,504

1990: 21 trials (Observational 8, Not applicable 1, Phase 4 1, Phase 3 5, Phase 2 4, Phase 1/2 1, Phase 1 1) 1991: 33 trials (Observational 9, Not applicable 2, Phase 3 7, Phase 2 7, Phase 1/2 1, Phase 1 7) 1992: 36 trials (Observational 6, Not applicable 4, Phase 3 15, Phase 2/3 1, Phase 2 6, Phase 1 4) 1993: 67 trials (Observational 14, Not applicable 7, Phase 3 26, Phase 2/3 2, Phase 2 13, Phase 1/2 1, Phase 1 4) 1994: 79 trials (Observational 13, Not applicable 5, Phase 3 32, Phase 2/3 1, Phase 2 14, Phase 1/2 5, Phase 1 9) 1995: 115 trials (Observational 19, Not applicable 3, Phase 4 1, Phase 3 32, Phase 2/3 1, Phase 2 33, Phase 1/2 5, Phase 1 21) 1996: 184 trials (Observational 27, Not applicable 6, Phase 3 54, Phase 2/3 3, Phase 2 61, Phase 1/2 7, Phase 1 26) 1997: 261 trials (Other 1, Observational 21, Not applicable 20, Phase 4 2, Phase 3 54, Phase 2/3 1, Phase 2 93, Phase 1/2 28, Phase 1 41) 1998: 405 trials (Observational 40, Not applicable 18, Phase 4 1, Phase 3 87, Phase 2/3 6, Phase 2 169, Phase 1/2 25, Phase 1 59) 1999: 510 trials (Observational 52, Not applicable 30, Phase 4 2, Phase 3 98, Phase 2/3 3, Phase 2 207, Phase 1/2 32, Phase 1 86) 2000: 633 trials (Observational 75, Not applicable 36, Phase 4 5, Phase 3 102, Phase 2/3 8, Phase 2 262, Phase 1/2 59, Phase 1 86) 2001: 673 trials (Observational 67, Not applicable 40, Phase 4 11, Phase 3 124, Phase 2/3 7, Phase 2 289, Phase 1/2 51, Phase 1 84) 2002: 846 trials (Observational 102, Not applicable 60, Phase 4 20, Phase 3 140, Phase 2/3 12, Phase 2 356, Phase 1/2 65, Phase 1 91) 2003: 1,046 trials (Observational 145, Not applicable 100, Phase 4 26, Phase 3 136, Phase 2/3 10, Phase 2 444, Phase 1/2 78, Phase 1 107) 2004: 1,266 trials (Other 1, Observational 183, Not applicable 120, Phase 4 22, Phase 3 157, Phase 2/3 14, Phase 2 531, Phase 1/2 92, Phase 1 146) 2005: 1,491 trials (Other 2, Observational 226, Not applicable 160, Phase 4 35, Phase 3 173, Phase 2/3 25, Phase 2 574, Phase 1/2 104, Phase 1 192) 2006: 1,748 trials (Other 2, Observational 264, Not applicable 182, Phase 4 42, Phase 3 202, Phase 2/3 26, Phase 2 689, Phase 1/2 123, Phase 1 218) 2007: 1,894 trials (Other 2, Observational 317, Not applicable 255, Phase 4 52, Phase 3 191, Phase 2/3 19, Phase 2 693, Phase 1/2 112, Phase 1 253) 2008: 2,007 trials (Observational 401, Not applicable 273, Phase 4 48, Phase 3 208, Phase 2/3 15, Phase 2 665, Phase 1/2 132, Phase 1 265) 2009: 2,125 trials (Other 2, Observational 401, Not applicable 336, Phase 4 40, Phase 3 206, Phase 2/3 36, Phase 2 621, Phase 1/2 163, Phase 1 320) 2010: 2,097 trials (Other 2, Observational 482, Not applicable 361, Phase 4 41, Phase 3 151, Phase 2/3 26, Phase 2 574, Phase 1/2 156, Phase 1 304) 2011: 2,134 trials (Other 1, Observational 436, Not applicable 415, Phase 4 53, Phase 3 182, Phase 2/3 32, Phase 2 622, Phase 1/2 105, Phase 1 288) 2012: 2,238 trials (Other 2, Observational 507, Not applicable 520, Phase 4 49, Phase 3 164, Phase 2/3 35, Phase 2 560, Phase 1/2 128, Phase 1 273) 2013: 2,266 trials (Other 1, Observational 481, Not applicable 536, Phase 4 60, Phase 3 187, Phase 2/3 27, Phase 2 563, Phase 1/2 120, Phase 1 291) 2014: 2,532 trials (Observational 558, Not applicable 645, Phase 4 54, Phase 3 195, Phase 2/3 32, Phase 2 563, Phase 1/2 157, Phase 1 328) 2015: 2,881 trials (Observational 629, Not applicable 785, Phase 4 69, Phase 3 227, Phase 2/3 35, Phase 2 607, Phase 1/2 178, Phase 1 351) 2016: 3,101 trials (Other 1, Observational 702, Not applicable 831, Phase 4 65, Phase 3 233, Phase 2/3 28, Phase 2 624, Phase 1/2 205, Phase 1 412) 2017: 3,173 trials (Other 1, Observational 714, Not applicable 854, Phase 4 46, Phase 3 186, Phase 2/3 35, Phase 2 712, Phase 1/2 234, Phase 1 391) 2018: 3,374 trials (Observational 765, Not applicable 931, Phase 4 58, Phase 3 247, Phase 2/3 47, Phase 2 717, Phase 1/2 222, Phase 1 387) 2019: 3,536 trials (Observational 916, Not applicable 898, Phase 4 60, Phase 3 227, Phase 2/3 36, Phase 2 765, Phase 1/2 228, Phase 1 406) 2020: 3,718 trials (Observational 980, Not applicable 964, Phase 4 52, Phase 3 245, Phase 2/3 29, Phase 2 822, Phase 1/2 201, Phase 1 425) 2021: 4,194 trials (Observational 1,105, Not applicable 1,152, Phase 4 54, Phase 3 264, Phase 2/3 44, Phase 2 898, Phase 1/2 228, Phase 1 449) 2022: 4,117 trials (Observational 1,132, Not applicable 1,155, Phase 4 61, Phase 3 234, Phase 2/3 52, Phase 2 847, Phase 1/2 225, Phase 1 411) 2023: 4,165 trials (Other 1, Observational 1,122, Not applicable 1,237, Phase 4 50, Phase 3 248, Phase 2/3 41, Phase 2 829, Phase 1/2 235, Phase 1 402) 2024: 4,504 trials (Observational 1,218, Not applicable 1,223, Phase 4 81, Phase 3 283, Phase 2/3 54, Phase 2 963, Phase 1/2 243, Phase 1 439) 2025: 4,272 trials (Observational 1,022, Not applicable 1,187, Phase 4 62, Phase 3 313, Phase 2/3 58, Phase 2 966, Phase 1/2 259, Phase 1 405)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 4,087
2025 4,272
2024 4,504
2023 4,165
2022 4,117
2021 4,194
2020 3,718
2019 3,536
2018 3,374
2017 3,173

Forecast of the full-year count, planned starts included, not rows of this table: about 5,100 trials starting in 2026 and about 4,500 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 8,757 trials still running at the 2026-10-09 snapshot; registered median of 35 months across 39,484 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Neoplasms by Site trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 8,455
Phase 1/2 4,529
Phase 2 18,513
Phase 2/3 856
Phase 3 5,992
Phase 4 1,302
Not applicable 16,636
Observational 16,030
Expanded access 186
Unknown 6

How many Neoplasms by Site trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3,728
Recruiting 10,937
Enrolling by invitation 409
Active, not recruiting 4,630
Available 44

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Neoplasms by Site trials? (6)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 2,029
AstraZeneca 648
Hoffmann-La Roche 532
Pfizer 485
Novartis Pharmaceuticals 482

Which drugs are being tested for Neoplasms by Site? (8)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
(nab)-paclitaxel 1,832
PEMBROLIZUMAB 1,524
"Capecitabine" 1,113
Cytoxan 1,051
NIVOLUMAB 962

Interventions as named in the registry (7)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Cisplatin 1 1,913
or carboplatin 1,857
Gemcitabine/Gemzar 1,450
Docetetaxel 1,402
Bevacizumab 1 1,381

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Neoplasms by Site trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 19,500 2,329
Malignant neoplasm progression 13,283 395
Vomiting 12,428 2,889
Febrile neutropenia 11,516 1,664
Nausea 10,723 2,689

Sub-conditions in MeSH (15)

MeSH descendants one level down with at least one trial, most trials first.

+5 more sub-conditions

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: publications, prevalence, and rare-disease identity.

Browse all condition evidence pages