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Condition (MeSH)

Thoracic Neoplasms

ClinicalTrials.gov lists 11,993 trials for Thoracic Neoplasms or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 319.

MeSH D013899 Neoplasms Neoplasm C04
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Phase 1 Phase 1 1,830 Phase 1/2 Phase 1/2 1,005 Phase 2 Phase 2 3,321 Phase 2/3 Phase 2/3 121 Phase 3 Phase 3 1,004 Phase 4 Phase 4 169 Not applicable Not applicable 2,006 Observational Observational 2,491 Phase 1 Phase 1 1,830 Phase 1/2 Phase 1/2 1,005 Phase 2 Phase 2 3,321 Phase 2/3 Phase 2/3 121 Phase 3 Phase 3 1,004 Phase 4 Phase 4 169 Not applicable Not applicable 2,006 Observational Observational 2,491

Trials per phase (log scale)

2 more sections with rows

113 of the 11,993 trials are tagged with Thoracic Neoplasms itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Thoracic Neoplasms trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 24 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access, Unknown)

Top of scale: 814

1990: 2 trials (Not applicable 1, Phase 2 1) 1991: 2 trials (Phase 2 1, Phase 1 1) 1992: 3 trials (Observational 2, Phase 2 1) 1993: 10 trials (Observational 2, Not applicable 1, Phase 3 2, Phase 2 3, Phase 1 2) 1994: 10 trials (Not applicable 1, Phase 3 6, Phase 2 2, Phase 1 1) 1995: 16 trials (Observational 3, Not applicable 1, Phase 3 4, Phase 2 3, Phase 1/2 1, Phase 1 4) 1996: 23 trials (Observational 2, Not applicable 1, Phase 3 4, Phase 2/3 1, Phase 2 10, Phase 1/2 1, Phase 1 4) 1997: 29 trials (Observational 2, Phase 3 7, Phase 2 9, Phase 1/2 4, Phase 1 7) 1998: 62 trials (Observational 6, Not applicable 2, Phase 3 18, Phase 2 25, Phase 1/2 3, Phase 1 8) 1999: 72 trials (Observational 3, Not applicable 3, Phase 3 19, Phase 2 29, Phase 1/2 3, Phase 1 15) 2000: 99 trials (Observational 10, Not applicable 3, Phase 4 1, Phase 3 17, Phase 2/3 2, Phase 2 39, Phase 1/2 6, Phase 1 21) 2001: 96 trials (Observational 6, Not applicable 6, Phase 3 21, Phase 2/3 4, Phase 2 41, Phase 1/2 6, Phase 1 12) 2002: 134 trials (Observational 14, Not applicable 5, Phase 4 4, Phase 3 23, Phase 2/3 3, Phase 2 63, Phase 1/2 6, Phase 1 16) 2003: 167 trials (Observational 20, Not applicable 8, Phase 4 1, Phase 3 15, Phase 2 82, Phase 1/2 17, Phase 1 24) 2004: 198 trials (Observational 23, Not applicable 20, Phase 4 2, Phase 3 18, Phase 2/3 1, Phase 2 89, Phase 1/2 14, Phase 1 31) 2005: 230 trials (Observational 41, Not applicable 14, Phase 4 1, Phase 3 23, Phase 2/3 5, Phase 2 105, Phase 1/2 12, Phase 1 29) 2006: 302 trials (Observational 34, Not applicable 26, Phase 4 4, Phase 3 37, Phase 2/3 3, Phase 2 142, Phase 1/2 20, Phase 1 36) 2007: 293 trials (Other 1, Observational 40, Not applicable 19, Phase 4 6, Phase 3 33, Phase 2/3 5, Phase 2 113, Phase 1/2 20, Phase 1 56) 2008: 331 trials (Observational 54, Not applicable 28, Phase 4 11, Phase 3 37, Phase 2/3 1, Phase 2 123, Phase 1/2 31, Phase 1 46) 2009: 355 trials (Observational 61, Not applicable 43, Phase 4 8, Phase 3 32, Phase 2/3 4, Phase 2 119, Phase 1/2 20, Phase 1 68) 2010: 293 trials (Observational 75, Not applicable 39, Phase 4 3, Phase 3 20, Phase 2/3 1, Phase 2 79, Phase 1/2 27, Phase 1 49) 2011: 302 trials (Observational 57, Not applicable 54, Phase 4 6, Phase 3 28, Phase 2/3 8, Phase 2 83, Phase 1/2 20, Phase 1 46) 2012: 320 trials (Other 1, Observational 87, Not applicable 55, Phase 4 3, Phase 3 18, Phase 2/3 2, Phase 2 93, Phase 1/2 24, Phase 1 37) 2013: 335 trials (Observational 76, Not applicable 55, Phase 4 5, Phase 3 28, Phase 2/3 4, Phase 2 98, Phase 1/2 17, Phase 1 52) 2014: 352 trials (Observational 77, Not applicable 69, Phase 4 8, Phase 3 28, Phase 2/3 6, Phase 2 78, Phase 1/2 26, Phase 1 60) 2015: 486 trials (Observational 93, Not applicable 89, Phase 4 7, Phase 3 38, Phase 2/3 8, Phase 2 119, Phase 1/2 51, Phase 1 81) 2016: 535 trials (Observational 128, Not applicable 95, Phase 4 7, Phase 3 43, Phase 2/3 2, Phase 2 116, Phase 1/2 49, Phase 1 95) 2017: 542 trials (Observational 125, Not applicable 92, Phase 4 10, Phase 3 30, Phase 2/3 6, Phase 2 125, Phase 1/2 65, Phase 1 89) 2018: 604 trials (Observational 129, Not applicable 128, Phase 4 8, Phase 3 47, Phase 2/3 6, Phase 2 141, Phase 1/2 53, Phase 1 92) 2019: 570 trials (Observational 137, Not applicable 97, Phase 4 14, Phase 3 38, Phase 2/3 4, Phase 2 130, Phase 1/2 49, Phase 1 101) 2020: 642 trials (Observational 169, Not applicable 94, Phase 4 7, Phase 3 48, Phase 2/3 5, Phase 2 169, Phase 1/2 54, Phase 1 96) 2021: 746 trials (Observational 176, Not applicable 139, Phase 4 9, Phase 3 52, Phase 2/3 3, Phase 2 182, Phase 1/2 73, Phase 1 112) 2022: 692 trials (Observational 159, Not applicable 141, Phase 4 7, Phase 3 36, Phase 2/3 5, Phase 2 173, Phase 1/2 69, Phase 1 102) 2023: 728 trials (Observational 188, Not applicable 164, Phase 4 7, Phase 3 49, Phase 2/3 5, Phase 2 146, Phase 1/2 67, Phase 1 102) 2024: 814 trials (Observational 186, Not applicable 175, Phase 4 12, Phase 3 65, Phase 2/3 5, Phase 2 186, Phase 1/2 55, Phase 1 130) 2025: 747 trials (Observational 174, Not applicable 137, Phase 4 3, Phase 3 64, Phase 2/3 11, Phase 2 186, Phase 1/2 61, Phase 1 111)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 730
2025 747
2024 814
2023 728
2022 692
2021 746
2020 642
2019 570
2018 604
2017 542

Forecast of the full-year count, planned starts included, not rows of this table: about 900 trials starting in 2026 and about 790 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 1,633 trials still running at the 2026-10-09 snapshot; registered median of 34 months across 6,373 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Thoracic Neoplasms trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1,830
Phase 1/2 1,005
Phase 2 3,321
Phase 2/3 121
Phase 3 1,004
Phase 4 169
Not applicable 2,006
Observational 2,491
Expanded access 45
Unknown 1

How many Thoracic Neoplasms trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 650
Recruiting 1,921
Enrolling by invitation 55
Active, not recruiting 845
Available 10

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Thoracic Neoplasms trials? (8)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 319
AstraZeneca 233
Eli Lilly and Company 160
Pfizer 139
Bristol-Myers Squibb 110

Which drugs are being tested for Thoracic Neoplasms? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
PEMBROLIZUMAB 490
(nab)-paclitaxel 468
NIVOLUMAB 256
DURVALUMAB 211
Osimertinib 186

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
or carboplatin 815
Cisplatin 1 571
Pemetrexe 493
Docetetaxel 395
Gemcitabine/Gemzar 298

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Thoracic Neoplasms trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 9,160 736
Malignant neoplasm progression 6,090 151
Dyspnoea 4,614 561
Febrile neutropenia 3,245 438
Anaemia 2,821 461

Which publications cover Thoracic Neoplasms? (95)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (4)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages