Condition (MeSH)
Common Variable Immunodeficiency
ClinicalTrials.gov lists 53 trials for Common Variable Immunodeficiency or a narrower condition beneath it. CSL Behring has the most among industry and government lead sponsors, with 5.
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Trials per phase
53 of the 53 trials are tagged with Common Variable Immunodeficiency itself; the rest are tagged with a narrower condition beneath it.
When did Common Variable Immunodeficiency trials start? (26)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 3 |
| 2025 | 3 |
| 2024 | 1 |
| 2023 | 2 |
| 2022 | 2 |
| 2021 | 2 |
| 2020 | 2 |
| 2019 | 1 |
| 2018 | 5 |
| 2017 | 2 |
Showing 10 of 26 earlier years.
No forecast is made for this condition: it averages 2.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 29 months across 29 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Common Variable Immunodeficiency trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 2 |
| Phase 2 | 11 |
| Phase 2/3 | 1 |
| Phase 3 | 10 |
| Phase 4 | 5 |
| Not applicable | 10 |
| Observational | 13 |
How many Common Variable Immunodeficiency trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 9 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 5 |
| Completed | 28 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Common Variable Immunodeficiency trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| CSL Behring | 5 |
| National Cancer Institute (NCI) | 4 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 4 |
| Azidus Brasil | 1 |
| BriovaRx Infusion Services | 1 |
Showing 5 of 6 sponsors.
Which drugs are being tested for Common Variable Immunodeficiency? (5)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Cytoxan | 4 |
| Busulfan | 4 |
| Leniolisib | 2 |
| MESNA | 2 |
| Prednisone | 2 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Globulin, Immune | 5 |
| Immunoglobulins Intravenous (Human) | 3 |
| Alemtuzumab s.c. | 2 |
| IR Tacrolimus | 2 |
| GVHD Prophylaxis | 2 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Common Variable Immunodeficiency trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Neutrophil count decreased | 11 | 1 |
| Platelet count decreased | 11 | 1 |
| White blood cell decreased | 8 | 1 |
| Infusion related reaction | 7 | 1 |
| Bacteremia | 6 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Common Variable Immunodeficiency? (61)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 61 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.