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Condition (MeSH)

Tooth, Nonvital

ClinicalTrials.gov lists 110 trials for Tooth, Nonvital or a narrower condition beneath it.

MeSH D019553 Stomatognathic Diseases C07
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Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 4 Phase 2/3 Phase 2/3 2 Phase 4 Phase 4 2 Not applicable Not applicable 91 Observational Observational 8 Phase 1 Phase 1 1 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 4 Phase 2/3 Phase 2/3 2 Phase 4 Phase 4 2 Not applicable Not applicable 91 Observational Observational 8

Trials per phase (log scale)

110 of the 110 trials are tagged with Tooth, Nonvital itself; the rest are tagged with a narrower condition beneath it.

Get the Tooth, Nonvital report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Tooth, Nonvital trials start? (20)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 20

1991: 1 trials (Observational 1) 2003: 1 trials (Phase 4 1) 2009: 1 trials (Observational 1) 2010: 1 trials (Observational 1) 2011: 1 trials (Not applicable 1) 2012: 1 trials (Not applicable 1) 2013: 1 trials (Not applicable 1) 2014: 1 trials (Not applicable 1) 2015: 2 trials (Not applicable 2) 2016: 4 trials (Not applicable 3, Phase 2 1) 2017: 5 trials (Observational 1, Not applicable 3, Phase 2 1) 2018: 10 trials (Not applicable 8, Phase 2/3 1, Phase 2 1) 2019: 20 trials (Not applicable 19, Phase 1 1) 2020: 13 trials (Observational 1, Not applicable 12) 2021: 9 trials (Observational 1, Not applicable 6, Phase 2/3 1, Phase 2 1) 2022: 7 trials (Not applicable 5, Phase 1/2 2) 2023: 8 trials (Not applicable 7, Phase 4 1) 2024: 12 trials (Not applicable 12) 2025: 5 trials (Observational 1, Not applicable 4)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 6
2025 5
2024 12
2023 8
2022 7
2021 9
2020 13
2019 20
2018 10
2017 5

Forecast of the full-year count, planned starts included, not rows of this table: about 6 trials starting in 2026 and about 5 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 33 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 53 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Tooth, Nonvital trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 1/2 2
Phase 2 4
Phase 2/3 2
Phase 4 2
Not applicable 91
Observational 8

How many Tooth, Nonvital trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 7
Recruiting 9
Active, not recruiting 5
Completed 49
Terminated 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Formocresol 2
Diode laser 2
0.5% Sodium hypochlorite 1
Low Level Laser Therapy 1
Resin Cement 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Tooth, Nonvital? (103)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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