Skip to content
Pharma Observatory a Scientist.com platform

Condition (MeSH)

Mobius Syndrome

ClinicalTrials.gov lists 3 trials for Mobius Syndrome or a narrower condition beneath it. National Human Genome Research Institute (NHGRI) has the most among industry and government lead sponsors, with 1.

MeSH D020331 Stomatognathic Diseases C07 C10 C11 C16 Listed by Orphanet as a rare disease
Email me this page as a PDF

Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Trials started per year Trials started per year 3 Trials by phase Trials by phase 1 Trials by recruitment status Trials by recruitment status 2 Lead sponsors Lead sponsors 1 Publications Publications 11 Prevalence Prevalence 15 Rare-disease identity Rare-disease identity 2 Trials started per year Trials started per year 3 Trials by phase Trials by phase 1 Trials by recruitment status Trials by recruitment status 2 Lead sponsors Lead sponsors 1 Publications Publications 11 Prevalence Prevalence 15 Rare-disease identity Rare-disease identity 2

Rows recorded per section

2 sections measured, none recorded · 1 not measured yet · 1 not computed

3 of the 3 trials are tagged with Mobius Syndrome itself; the rest are tagged with a narrower condition beneath it.

Get the Mobius Syndrome report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Mobius Syndrome trials start? (3)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Observational

Top of scale: 1

2002: 1 trials (Observational 1) 2004: 1 trials (Observational 1) 2005: 1 trials (Observational 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2005 1
2004 1
2002 1

No forecast is made for this condition: it averages 0.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 3 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Mobius Syndrome trials in? (1)

Shown in this order: phase order.

Trials by phase
Phase Trials
Observational 3

How many Mobius Syndrome trials are recruiting? (2)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 1
Completed 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Mobius Syndrome trials? (1)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Human Genome Research Institute (NHGRI) 1

Which publications cover Mobius Syndrome? (11)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Inability to move one's face dampens facial expression perception. Cortex; a journal devoted to the study of the nervous system and behavior 2023 Yes
A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome. Nature communications 2017 Yes
Identification of STAC3 variants in non-Native American families with overlapping features of Carey-Fineman-Ziter syndrome and Moebius syndrome. American journal of medical genetics. Part A 2017 Yes
Oral motor assessment in individuals with Moebius syndrome. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Yes
Diagnostic distinctions and genetic analysis of patients diagnosed with moebius syndrome. Ophthalmology 2014 Yes

Showing 5 of 11 publications.

Start your 14-day trial Email me all 11 publications as a PDF

Prevalence (15)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Moebius syndrome Point prevalence 1-9 / 100 000 Worldwide Not stated Unspecified
Moebius syndrome Point prevalence 1-9 / 100 000 Worldwide Not stated Exact
Moebius syndrome Cases families Worldwide Not stated Exact
Moebius syndrome Point prevalence 1-9 / 100 000 Worldwide Not stated Exact
Moebius syndrome Prevalence at birth <1 / 1 000 000 Italy Not stated Unspecified

Showing 5 of 15 prevalence observations.

Start your 14-day trial Email me all 15 prevalence observations as a PDF

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Moebius syndrome 570 Exact Orphadata Science knowledge files, Product 1
Moebius syndrome 570 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.

Not computed for conditions with fewer than 10 trials: drugs tested.

Browse all condition evidence pages