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Condition (MeSH)

Central Nervous System Helminthiasis

ClinicalTrials.gov lists 20 trials for Central Nervous System Helminthiasis or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 4.

MeSH D020809 Infections C01 C10
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Phase 1 Phase 1 4 Phase 2/3 Phase 2/3 3 Phase 3 Phase 3 4 Phase 4 Phase 4 1 Not applicable Not applicable 2 Observational Observational 6 Phase 1 Phase 1 4 Phase 2/3 Phase 2/3 3 Phase 3 Phase 3 4 Phase 4 Phase 4 1 Not applicable Not applicable 2 Observational Observational 6

Trials per phase

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When did Central Nervous System Helminthiasis trials start? (14)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 3

2001: 1 trials (Phase 3 1) 2006: 1 trials (Phase 3 1) 2007: 2 trials (Phase 1 2) 2010: 1 trials (Phase 2/3 1) 2011: 1 trials (Not applicable 1) 2014: 3 trials (Observational 1, Phase 3 1, Phase 1 1) 2015: 1 trials (Phase 2/3 1) 2016: 2 trials (Phase 3 1, Phase 1 1) 2018: 1 trials (Observational 1) 2019: 2 trials (Observational 2) 2021: 1 trials (Observational 1) 2024: 1 trials (Phase 4 1) 2025: 1 trials (Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 1
2024 1
2021 1
2019 2
2018 1
2016 2
2015 1
2014 3
2011 1

No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 20 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Central Nervous System Helminthiasis trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 4
Phase 2/3 3
Phase 3 4
Phase 4 1
Not applicable 2
Observational 6

How many Central Nervous System Helminthiasis trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 1
Completed 11
Terminated 3
Withdrawn 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Central Nervous System Helminthiasis trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 4
National Institute of Mental Health (NIMH) 2
Cephas Health Research Initiative Inc, Ibadan, Nigeria 1

Which drugs are being tested for Central Nervous System Helminthiasis? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Albendazole 4
Oxfendazole 2
Omeprazole 20 mg 1
Praziquantel 1
Niclosamide 1

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Albendazole and praziquantel 2
Dexamethasone/Dexamethasone acetate 2
28 days of albendazole 15 mg/kg/day 1
Oxfendazole three doses 1
Oxfendazole single dose 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Central Nervous System Helminthiasis trials report? (1)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Prolonged hospitalization 4 1

Which publications cover Central Nervous System Helminthiasis? (1)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Antiplatelet Drug Use and Cerebral Microbleeds: A Meta-analysis of Published Studies. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2015 Yes

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

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