Skip to content
Pharma Observatory a Scientist.com platform

Condition (MeSH)

Central Nervous System Parasitic Infections

ClinicalTrials.gov lists 53 trials for Central Nervous System Parasitic Infections or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 9.

MeSH D020807 Infections C01 C10
Email me this page as a PDF

Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Phase 1 Phase 1 8 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 5 Phase 2/3 Phase 2/3 4 Phase 3 Phase 3 10 Phase 4 Phase 4 1 Not applicable Not applicable 10 Observational Observational 12 Phase 1 Phase 1 8 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 5 Phase 2/3 Phase 2/3 4 Phase 3 Phase 3 10 Phase 4 Phase 4 1 Not applicable Not applicable 10 Observational Observational 12

Trials per phase

1 more section with rows

Get the Central Nervous System Parasitic Infections report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Central Nervous System Parasitic Infections trials start? (22)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 4

2001: 1 trials (Phase 3 1) 2003: 1 trials (Phase 3 1) 2004: 1 trials (Phase 3 1) 2006: 2 trials (Phase 3 1, Phase 1 1) 2007: 4 trials (Observational 1, Phase 2/3 1, Phase 1 2) 2008: 1 trials (Not applicable 1) 2009: 1 trials (Observational 1) 2010: 3 trials (Phase 3 2, Phase 2/3 1) 2011: 2 trials (Not applicable 1, Phase 2 1) 2012: 1 trials (Phase 3 1) 2013: 1 trials (Phase 1/2 1) 2014: 4 trials (Observational 1, Phase 3 1, Phase 2 1, Phase 1 1) 2015: 1 trials (Phase 2/3 1) 2016: 3 trials (Not applicable 1, Phase 3 1, Phase 1 1) 2018: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 2019: 2 trials (Observational 2) 2021: 3 trials (Observational 1, Not applicable 1, Phase 2 1) 2022: 2 trials (Other 1, Phase 1/2 1) 2023: 1 trials (Observational 1) 2024: 2 trials (Observational 1, Phase 4 1) 2025: 2 trials (Observational 1, Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 2
2024 2
2023 1
2022 2
2021 3
2019 2
2018 3
2016 3
2015 1

No forecast is made for this condition: it averages 1.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Central Nervous System Parasitic Infections trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 8
Phase 1/2 2
Phase 2 5
Phase 2/3 4
Phase 3 10
Phase 4 1
Not applicable 10
Observational 12
Unknown 1

How many Central Nervous System Parasitic Infections trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 3
Completed 36
Terminated 4
Withdrawn 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Central Nervous System Parasitic Infections trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 9
National Institute of Mental Health (NIMH) 2
U.S. Army Medical Research and Development Command 2
Cephas Health Research Initiative Inc, Ibadan, Nigeria 1

Which drugs are being tested for Central Nervous System Parasitic Infections? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Pyrimethamine 7
Calcium Leucovorin 5
Albendazole 4
Oxfendazole 2
Atovaquone 2

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Dexamethasone/Dexamethasone acetate 3
Albendazole and praziquantel 2
Intravenous Artesunate 2
Levetiracetam XR 2
Clindamycin Gel 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Central Nervous System Parasitic Infections trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
death 6 1
elevated AST 5 1
Prolonged hospitalization 4 1
Sepsis 4 1
Respiratory problems from ventilator 3 1

Which publications cover Central Nervous System Parasitic Infections? (2)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Subarachnoid basal neurocysticercosis: a focus on the most severe form of the disease. Expert review of anti-infective therapy 2011 Yes
Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster. Transactions of the Royal Society of Tropical Medicine and Hygiene 2000 No

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages