Condition (MeSH)
Insomnia, Fatal Familial
ClinicalTrials.gov lists 17 trials for Insomnia, Fatal Familial or a narrower condition beneath it.
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Trials per phase
17 of the 17 trials are tagged with Insomnia, Fatal Familial itself; the rest are tagged with a narrower condition beneath it.
When did Insomnia, Fatal Familial trials start? (12)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 2 |
| 2024 | 2 |
| 2023 | 1 |
| 2021 | 1 |
| 2019 | 1 |
| 2018 | 1 |
| 2017 | 2 |
| 2015 | 1 |
| 2011 | 2 |
Showing 10 of 12 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Insomnia, Fatal Familial trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 1 |
| Phase 2 | 3 |
| Not applicable | 7 |
| Observational | 5 |
How many Insomnia, Fatal Familial trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 4 |
| Completed | 10 |
| Unknown status | 2 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Insomnia, Fatal Familial trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Faculty Hospital Kralovske Vinohrady | 1 |
| Regeneron Pharmaceuticals | 1 |
| Sheba Medical Center | 1 |
| xCures | 1 |
Which drugs are being tested for Insomnia, Fatal Familial? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Quinacrine | 1 |
Interventions as named in the registry (7)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| [PRP] platelet rich plasma | 2 |
| NaCl 0.9% NS | 1 |
| PrP-siRNA | 1 |
| Hyaluronic Acid (HA) and Platelet rich plasma | 1 |
| ALN-6457 | 1 |
Showing 5 of 7 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Insomnia, Fatal Familial trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Death | 29 | 1 |
| Fall | 2 | 1 |
| Hemorrhage | 2 | 1 |
| Post-LP Dizziness | 2 | 1 |
| Post-LP headache | 2 | 1 |
Showing 5 of 10 adverse events.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Fatal familial insomnia | Cases families | Worldwide | Not stated | Exact | |
| Fatal familial insomnia | Cases families | Worldwide | Not stated | Exact | |
| Fatal familial insomnia | Point prevalence | <1 / 1 000 000 | Worldwide | Not stated | Exact |
| Fatal familial insomnia | Point prevalence | <1 / 1 000 000 | Worldwide | Not stated | Unspecified |
| Fatal familial insomnia | Cases families | Worldwide | Not stated | Unspecified |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Fatal familial insomnia | 466 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Fatal familial insomnia | 466 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: publications and sub-conditions in mesh.