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Condition (MeSH)

Hearing Loss, Unilateral

ClinicalTrials.gov lists 49 trials for Hearing Loss, Unilateral or a narrower condition beneath it.

MeSH D046088 Otorhinolaryngologic Diseases C09 C10 C23
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Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Phase 3 Phase 3 2 Phase 4 Phase 4 2 Not applicable Not applicable 30 Observational Observational 13 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 1 Phase 3 Phase 3 2 Phase 4 Phase 4 2 Not applicable Not applicable 30 Observational Observational 13

Trials per phase (log scale)

49 of the 49 trials are tagged with Hearing Loss, Unilateral itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hearing Loss, Unilateral trials start? (18)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 9

2004: 1 trials (Observational 1) 2009: 1 trials (Not applicable 1) 2010: 2 trials (Not applicable 1, Phase 4 1) 2011: 1 trials (Observational 1) 2012: 1 trials (Not applicable 1) 2013: 3 trials (Observational 1, Not applicable 1, Phase 4 1) 2014: 3 trials (Not applicable 2, Phase 1/2 1) 2015: 4 trials (Not applicable 3, Phase 3 1) 2016: 1 trials (Phase 3 1) 2017: 5 trials (Observational 1, Not applicable 4) 2018: 4 trials (Observational 1, Not applicable 3) 2019: 2 trials (Observational 2) 2020: 2 trials (Observational 1, Not applicable 1) 2021: 4 trials (Observational 2, Not applicable 2) 2022: 9 trials (Observational 1, Not applicable 7, Phase 2 1) 2023: 2 trials (Not applicable 2) 2025: 2 trials (Observational 1, Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 2
2023 2
2022 9
2021 4
2020 2
2019 2
2018 4
2017 5
2016 1

No forecast is made for this condition: it averages 3.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 25 months across 31 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hearing Loss, Unilateral trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1/2 1
Phase 2 1
Phase 3 2
Phase 4 2
Not applicable 30
Observational 13

How many Hearing Loss, Unilateral trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 5
Enrolling by invitation 1
Active, not recruiting 4
Completed 27
Terminated 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hearing Loss, Unilateral trials? (8)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Oticon Medical 5
Sonitus Medical Inc 5
Cochlear 3
Med-El Corporation 3
Sonova AG 2

Which drugs are being tested for Hearing Loss, Unilateral? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
PREDNISOLONE 1

Interventions as named in the registry (5)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
AM-111 0.8 mg/ml 2
AM-111 0.4 mg/ml 2
Control (placebo) group 1
CGF166 1
AC102 gel 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hearing Loss, Unilateral trials report? (5)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Acute kidney injury 1 1
Chest pain 1 1
Sepsis 1 1
Vertigo 1 1
swelling and purulent drainage from post-auricular incision 1 1

Which publications cover Hearing Loss, Unilateral? (61)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Anatomy-based fitting improves speech perception in noise for cochlear implant recipients with single-sided deafness. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2025 Yes
The Relationship between Chronic Unilateral Hearing Loss, Balance Function, and Falls Is Not Informed by Vestibular Status. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2025 Yes
Auditory Cortical Plasticity in Patients with Single-Sided Deafness Before and After Cochlear Implantation. Journal of the Association for Research in Otolaryngology : JARO 2024 Yes
Two-Year Outcomes of Cochlear Implant Use for Children With Unilateral Hearing Loss: Benefits and Comparison to Children With Normal Hearing. Ear and hearing 2023 Yes
Hearing Aid Use in Children With Unilateral Hearing Loss: A Randomized Crossover Clinical Trial. The Laryngoscope 2022 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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