Condition (MeSH)
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
ClinicalTrials.gov lists 60 trials for Multiple Acyl Coenzyme A Dehydrogenase Deficiency or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 22.
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Trials per phase (log scale)
60 of the 60 trials are tagged with Multiple Acyl Coenzyme A Dehydrogenase Deficiency itself; the rest are tagged with a narrower condition beneath it.
When did Multiple Acyl Coenzyme A Dehydrogenase Deficiency trials start? (16)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2024 | 1 |
| 2023 | 1 |
| 2022 | 1 |
| 2018 | 2 |
| 2017 | 1 |
| 2016 | 2 |
| 2014 | 1 |
| 2012 | 3 |
| 2010 | 1 |
Showing 10 of 16 earlier years.
No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 60 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Multiple Acyl Coenzyme A Dehydrogenase Deficiency trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 12 |
| Phase 1/2 | 1 |
| Phase 2 | 7 |
| Phase 3 | 5 |
| Phase 4 | 4 |
| Not applicable | 25 |
| Observational | 6 |
How many Multiple Acyl Coenzyme A Dehydrogenase Deficiency trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 2 |
| Completed | 49 |
| Terminated | 1 |
| Withdrawn | 2 |
| Unknown status | 6 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Multiple Acyl Coenzyme A Dehydrogenase Deficiency trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | 22 |
| Hoffmann-La Roche | 12 |
| Astra USA | 1 |
| Chiron Corporation | 1 |
| Ionis Pharmaceuticals, Inc. | 1 |
Showing 5 of 6 sponsors.
Which drugs are being tested for Multiple Acyl Coenzyme A Dehydrogenase Deficiency? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Ganciclovir | 42 |
| Foscarnet | 8 |
| Zidovudine | 4 |
| Sevirumab | 2 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Valganciclovir | 7 |
| Sagramostim | 2 |
| Gemcitabine/Gemzar | 1 |
| Valaciclovir/Aciclovir | 1 |
| Valganciclovir/Ganciclovir | 1 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Multiple Acyl Coenzyme A Dehydrogenase Deficiency trials report? (2)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Kidney stone | 1 | 1 |
| Pericardial effusion | 1 | 1 |
Which publications cover Multiple Acyl Coenzyme A Dehydrogenase Deficiency? (1)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| State of the art in muscle lipid diseases. | Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology | 2010 | No |
Prevalence (8)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Multiple acyl-CoA dehydrogenase deficiency | Prevalence at birth | 1-9 / 1 000 000 | United States | US | Exact |
| Multiple acyl-CoA dehydrogenase deficiency | Prevalence at birth | 1-9 / 1 000 000 | United States | US | Exact |
| Multiple acyl-CoA dehydrogenase deficiency | Point prevalence | 1-9 / 1 000 000 | Europe | Not stated | Exact |
| Multiple acyl-CoA dehydrogenase deficiency | Prevalence at birth | 1-9 / 100 000 | Specific population | Not stated | Exact |
| Multiple acyl-CoA dehydrogenase deficiency | Prevalence at birth | 1-9 / 1 000 000 | Israel | Not stated | Exact |
Showing 5 of 8 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Multiple acyl-CoA dehydrogenase deficiency | 26791 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Multiple acyl-CoA dehydrogenase deficiency | 26791 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.