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Condition (MeSH)

Periodontal Atrophy

ClinicalTrials.gov lists 750 trials for Periodontal Atrophy or a narrower condition beneath it.

MeSH D055093 Stomatognathic Diseases C07
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Phase 1 Phase 1 20 Phase 1/2 Phase 1/2 12 Phase 2 Phase 2 15 Phase 2/3 Phase 2/3 9 Phase 3 Phase 3 15 Phase 4 Phase 4 40 Not applicable Not applicable 557 Observational Observational 81 Phase 1 Phase 1 20 Phase 1/2 Phase 1/2 12 Phase 2 Phase 2 15 Phase 2/3 Phase 2/3 9 Phase 3 Phase 3 15 Phase 4 Phase 4 40 Not applicable Not applicable 557 Observational Observational 81

Trials per phase (log scale)

1 more section with rows

5 of the 750 trials are tagged with Periodontal Atrophy itself; the rest are tagged with a narrower condition beneath it.

Get the Periodontal Atrophy report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Periodontal Atrophy trials start? (25)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 79

1999: 1 trials (Not applicable 1) 2002: 2 trials (Phase 4 1, Phase 1/2 1) 2004: 1 trials (Not applicable 1) 2005: 3 trials (Not applicable 2, Phase 1/2 1) 2006: 1 trials (Phase 4 1) 2007: 4 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 1) 2008: 10 trials (Not applicable 3, Phase 4 2, Phase 3 1, Phase 1/2 3, Phase 1 1) 2009: 7 trials (Observational 2, Not applicable 3, Phase 3 1, Phase 2 1) 2010: 12 trials (Not applicable 8, Phase 4 3, Phase 2 1) 2011: 12 trials (Observational 1, Not applicable 9, Phase 4 2) 2012: 14 trials (Other 1, Not applicable 9, Phase 3 1, Phase 2/3 1, Phase 2 1, Phase 1/2 1) 2013: 17 trials (Observational 1, Not applicable 9, Phase 4 4, Phase 2/3 1, Phase 2 2) 2014: 34 trials (Observational 3, Not applicable 23, Phase 4 6, Phase 1/2 1, Phase 1 1) 2015: 38 trials (Observational 1, Not applicable 30, Phase 4 3, Phase 3 1, Phase 2/3 1, Phase 1/2 1, Phase 1 1) 2016: 35 trials (Observational 2, Not applicable 28, Phase 4 2, Phase 1 3) 2017: 50 trials (Observational 7, Not applicable 37, Phase 4 1, Phase 2/3 1, Phase 2 3, Phase 1 1) 2018: 52 trials (Observational 4, Not applicable 41, Phase 4 1, Phase 3 2, Phase 2/3 1, Phase 1/2 1, Phase 1 2) 2019: 53 trials (Observational 7, Not applicable 34, Phase 4 3, Phase 3 2, Phase 2 4, Phase 1/2 1, Phase 1 2) 2020: 31 trials (Observational 5, Not applicable 21, Phase 4 3, Phase 3 1, Phase 2/3 1) 2021: 39 trials (Observational 5, Not applicable 32, Phase 4 1, Phase 1 1) 2022: 62 trials (Observational 7, Not applicable 48, Phase 4 2, Phase 3 2, Phase 1 3) 2023: 65 trials (Observational 8, Not applicable 54, Phase 4 1, Phase 3 1, Phase 1 1) 2024: 79 trials (Observational 11, Not applicable 63, Phase 4 2, Phase 3 1, Phase 1/2 1, Phase 1 1) 2025: 73 trials (Observational 5, Not applicable 61, Phase 4 2, Phase 2/3 1, Phase 2 2, Phase 1 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 52
2025 73
2024 79
2023 65
2022 62
2021 39
2020 31
2019 53
2018 52
2017 50

Forecast of the full-year count, planned starts included, not rows of this table: about 68 trials starting in 2026 and about 68 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 35 months from start to primary completion across 70 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 440 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Periodontal Atrophy trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 20
Phase 1/2 12
Phase 2 15
Phase 2/3 9
Phase 3 15
Phase 4 40
Not applicable 557
Observational 81
Unknown 1

How many Periodontal Atrophy trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 46
Recruiting 89
Enrolling by invitation 11
Active, not recruiting 29
Completed 410

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Periodontal Atrophy? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Platelet Rich Fibrin 16

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Connective tissue graft 20
Low Level Laser Therapy 8
Hyaluronic acid 1% 7
Mucograft 5
subepithelial connective tissue graft 5

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Periodontal Atrophy trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Vehicle accident 2 1
Appendicitis 1 1
Assault 1 1
Assault injury 1 1
Basal cell carcinoma basal 1 1

Which publications cover Periodontal Atrophy? (4)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, and rare-disease identity.

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