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Condition (MeSH)

Carney Complex

ClinicalTrials.gov lists 8 trials for Carney Complex or a narrower condition beneath it.

MeSH D056733 Neoplasms Neoplasm C04 C14 C16 Listed by Orphanet as a rare disease
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Phase 2 Phase 2 1 Not applicable Not applicable 3 Observational Observational 4 Phase 2 Phase 2 1 Not applicable Not applicable 3 Observational Observational 4

Trials per phase

8 of the 8 trials are tagged with Carney Complex itself; the rest are tagged with a narrower condition beneath it.

Get the Carney Complex report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Carney Complex trials start? (7)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 2
  • Not applicable
  • Observational

Top of scale: 2

1995: 1 trials (Observational 1) 2008: 1 trials (Observational 1) 2012: 1 trials (Phase 2 1) 2017: 1 trials (Observational 1) 2020: 1 trials (Not applicable 1) 2022: 2 trials (Observational 1, Not applicable 1) 2023: 1 trials (Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2023 1
2022 2
2020 1
2017 1
2012 1
2008 1
1995 1

No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 8 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Carney Complex trials in? (3)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 2 1
Not applicable 3
Observational 4

How many Carney Complex trials are recruiting? (2)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 2
Completed 6

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Carney Complex trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 1
National Cancer Institute (NCI) 1

Which serious adverse events do Carney Complex trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Abdominal Pain - Grade 3 (Unrelated) 3 1
Abdominal Distension - Grade 3 (Unrelated) 1 1
Abdominal Pain - Grade 3 (Unlikely Related) 1 1
Constipation - Grade 2 (Unrelated) 1 1
Edema Limbs - Grade 2 (Unlikely Related) 1 1

Which publications cover Carney Complex? (5)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Carney complex predisposes to breast cancer: prospective study of 50 women. European journal of endocrinology 2024 Yes
Predicting the risk of cardiac myxoma in Carney complex. Genetics in medicine : official journal of the American College of Medical Genetics 2021 Yes
Frequency and Incidence of Carney Complex Manifestations: A Prospective Multicenter Study With a Three-Year Follow-Up. The Journal of clinical endocrinology and metabolism 2020 Yes
Hepato-pancreato-biliary lesions are present in both Carney complex and McCune Albright syndrome: comments on P. Salpea and C. Stratakis. Molecular and cellular endocrinology 2014 Yes
Clinical features and genetic predisposition to hereditary nonmedullary thyroid cancer. Thyroid : official journal of the American Thyroid Association 2009 No

Prevalence (6)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Carney complex Cases families Worldwide Not stated Exact
Carney complex Cases families Worldwide Not stated Exact
Carney complex Point prevalence <1 / 1 000 000 Worldwide Not stated Unspecified
Carney complex Point prevalence <1 / 1 000 000 Worldwide Not stated Exact
Carney complex Point prevalence <1 / 1 000 000 Worldwide Not stated Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Carney complex 1359 Exact Orphanet Rare Disease Ontology (ORDO)
Carney complex 1359 Exact Orphadata Science knowledge files, Product 1

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

Not computed for conditions with fewer than 10 trials: drugs tested.

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