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Condition (MeSH)

Euglenozoa Infections

ClinicalTrials.gov lists 301 trials for Euglenozoa Infections or a narrower condition beneath it. U.S. Army Medical Research and Development Command has the most among industry and government lead sponsors, with 16.

MeSH D056986 Infections C01
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Phase 1 Phase 1 29 Phase 1/2 Phase 1/2 10 Phase 2 Phase 2 59 Phase 2/3 Phase 2/3 17 Phase 3 Phase 3 49 Phase 4 Phase 4 20 Not applicable Not applicable 39 Observational Observational 75 Phase 1 Phase 1 29 Phase 1/2 Phase 1/2 10 Phase 2 Phase 2 59 Phase 2/3 Phase 2/3 17 Phase 3 Phase 3 49 Phase 4 Phase 4 20 Not applicable Not applicable 39 Observational Observational 75

Trials per phase

1 more section with rows

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When did Euglenozoa Infections trials start? (29)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 20

1993: 1 trials (Observational 1) 1995: 2 trials (Observational 1, Phase 2 1) 1999: 2 trials (Phase 3 1, Phase 1 1) 2001: 4 trials (Observational 2, Phase 3 1, Phase 2 1) 2002: 2 trials (Phase 2/3 1, Phase 2 1) 2003: 7 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 3 2, Phase 2 2) 2004: 8 trials (Phase 3 2, Phase 2 2, Phase 1/2 2, Phase 1 2) 2005: 7 trials (Phase 3 1, Phase 2 3, Phase 1/2 2, Phase 1 1) 2006: 13 trials (Observational 4, Not applicable 1, Phase 4 1, Phase 3 4, Phase 2 3) 2007: 16 trials (Observational 1, Not applicable 4, Phase 4 3, Phase 3 3, Phase 2 4, Phase 1 1) 2008: 12 trials (Not applicable 1, Phase 4 1, Phase 3 5, Phase 2/3 3, Phase 2 2) 2009: 11 trials (Observational 2, Not applicable 1, Phase 4 3, Phase 3 1, Phase 2 4) 2010: 8 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 5) 2011: 19 trials (Observational 6, Not applicable 1, Phase 4 4, Phase 3 1, Phase 2/3 1, Phase 2 4, Phase 1 2) 2012: 13 trials (Observational 2, Not applicable 4, Phase 4 2, Phase 3 1, Phase 2/3 2, Phase 1 2) 2013: 16 trials (Observational 4, Not applicable 2, Phase 4 2, Phase 3 1, Phase 2/3 1, Phase 2 3, Phase 1 3) 2014: 15 trials (Observational 1, Not applicable 3, Phase 4 2, Phase 3 3, Phase 2 3, Phase 1/2 1, Phase 1 2) 2015: 14 trials (Observational 7, Phase 3 1, Phase 2/3 1, Phase 2 3, Phase 1 2) 2016: 10 trials (Observational 2, Not applicable 1, Phase 3 2, Phase 2/3 1, Phase 2 4) 2017: 12 trials (Observational 3, Not applicable 3, Phase 3 3, Phase 2/3 1, Phase 2 2) 2018: 14 trials (Observational 6, Not applicable 2, Phase 3 1, Phase 2 2, Phase 1 3) 2019: 20 trials (Observational 7, Not applicable 2, Phase 4 1, Phase 3 2, Phase 2/3 2, Phase 2 1, Phase 1/2 2, Phase 1 3) 2020: 7 trials (Observational 3, Not applicable 1, Phase 2 1, Phase 1 2) 2021: 14 trials (Observational 3, Not applicable 1, Phase 3 5, Phase 2/3 1, Phase 2 2, Phase 1/2 2) 2022: 11 trials (Observational 5, Not applicable 2, Phase 3 2, Phase 2/3 2) 2023: 8 trials (Observational 3, Not applicable 1, Phase 2/3 1, Phase 1 3) 2024: 5 trials (Observational 3, Not applicable 1, Phase 3 1) 2025: 15 trials (Observational 3, Not applicable 4, Phase 3 2, Phase 2 5, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 6
2025 15
2024 5
2023 8
2022 11
2021 14
2020 7
2019 20
2018 14
2017 12

Forecast of the full-year count, planned starts included, not rows of this table: about 6 trials starting in 2026 and about 10 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 33 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 21 months across 207 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Euglenozoa Infections trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 29
Phase 1/2 10
Phase 2 59
Phase 2/3 17
Phase 3 49
Phase 4 20
Not applicable 39
Observational 75
Expanded access 3

How many Euglenozoa Infections trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 8
Recruiting 20
Active, not recruiting 5
Available 1
Completed 200

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Euglenozoa Infections trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
U.S. Army Medical Research and Development Command 16
National Institute of Allergy and Infectious Diseases (NIAID) 8
Bayer 7

Which drugs are being tested for Euglenozoa Infections? (10)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Miltefosine 25
Meglumine Antimoniate 21
Benznidazole 17
Nifurtimox 11
Paromomycin 10

Interventions as named in the registry (5)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
liposomal Amphotericine B 10
Sodium Stibogluconate 10
WR 279,396 6
Leish-111f + MPL-SE vaccine 4
E1224 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Euglenozoa Infections trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Cardiac failure 74 1
Acute kidney injury 63 2
Ischaemic stroke 56 1
Pneumonia 54 4
Hypotension 52 1

Sub-conditions in MeSH (2)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: publications, prevalence, and rare-disease identity.

Browse all condition evidence pages